Journal article

Publication year: 2006

Pages: 429-438

Journal: Zeitschrift für Rheumatologie

Volume number: 65

Issue number: 5

ISSN: 0340-1855

eISSN: 1435-1250

DOI Link: https://doi.org/10.1007/s00393-006-0076-x

Publisher: Springer

Abstract: 
The connective tissue disease systemic sclerosis (SSc is still a challenge to every rheumatologist. SSc is characterized by progressing fibrosis of the skin and internal organs, abnormal activation of the immune system and distinct changes in microcirculation. Although it is a rare disease with a prevalence of about 20:100,000, one may come across it in daily practice. SSc is classified into limited and diffuse forms. Both entities usually involve internal organs. Life expectancy is limited and depends predominantly on the extent of the organs involved. Therefore, it is essential to diagnose and to identify and closely monitor the organs involved.

Harvard Citation style: Saar, P. and Mueller-Ladner, U. (2006) Systemic sclerosis -: a challenge in rheumatology, Zeitschrift für Rheumatologie, 65(5), pp. 429-438. https://doi.org/10.1007/s00393-006-0076-x

APA Citation style: Saar, P., & Mueller-Ladner, U. (2006). Systemic sclerosis -: a challenge in rheumatology. Zeitschrift für Rheumatologie. 65(5), 429-438. https://doi.org/10.1007/s00393-006-0076-x