Journalartikel

Jahr der Veröffentlichung: 2006

Seiten: 261-264

Zeitschrift: Autoimmunity

Bandnummer: 39

Heftnummer: 3

ISSN: 0891-6934

eISSN: 1607-842X

DOI Link: https://doi.org/10.1080/08916930600623874

Verlag: Taylor and Francis Group

Abstract: 
Idiopathic inflammatory myopathies (IM), including dermatomyositis (DM) and polymyositis (PM), are a group of systemic rheumatologic diseases of unknown etiology characterized by chronic myositis. Antisynthetase antibodies such as the anti-Jo-1 antibody are known to be highly specific for inflammatory myopathies. Patients with this antibody frequently show a combination of symptoms including interstitial lung disease, fever, polyarthritis, myositis, Raynaud's phenomenon and '' mechanic's hands ''. In the management of PM with anti-Jo-1 antibody, immunosuppressive agents are used to control the disease. Leflunomide is a new immunosuppressive drug recently introduced in the treatment of rheumatoid and psoriatic arthritis. Here, we report two cases of female patients with PM and anti-Jo-1 antibodies, who were successfully treated with leflunomide.

Harvard-Zitierstil: Lange, U., Piegsa, M., Mueller-Ladner, U. and Strunk, J. (2006) Anti-Jo-1 antibody positive polymyositis-successful therapy with leflunomide, Autoimmunity, 39(3), pp. 261-264. https://doi.org/10.1080/08916930600623874

APA-Zitierstil: Lange, U., Piegsa, M., Mueller-Ladner, U., & Strunk, J. (2006). Anti-Jo-1 antibody positive polymyositis-successful therapy with leflunomide. Autoimmunity. 39(3), 261-264. https://doi.org/10.1080/08916930600623874