Journalartikel

Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans


AutorenlisteKoebnick, Corinna; Garcia, Ada L.; Dagnelie, Pieter C.; Strassner, Carola; Lindemans, Jan; Katz, Norbert; Leitzmann, Claus; Hoffmann, Ingrid

Jahr der Veröffentlichung2005

Seiten2372-2378

ZeitschriftThe Journal of Nutrition

Bandnummer135

Heftnummer10

ISSN0022-3166

eISSN1541-6100

Open Access StatusBronze

DOI Linkhttps://doi.org/10.1093/jn/135.10.2372

VerlagElsevier


Abstract
High consumption of vegetables and fruits is associated with reduced risk for cardiovascular disease. However, little information is available about diets based predominantly on consumption of fruits and their health consequences. We investigated the effects of an extremely high dietary intake of raw vegetables and fruits (70-100% raw food) on serum lipids and plasma vitamin B-12, folate, and total homocysteine (tHcy). In a cross-sectional study, the lipid, folate, vitamin B-12, and tHcy status of 201 adherents to a raw food diet (94 men and 107 women) were examined. The participants consumed similar to 1500-1800 g raw food of plant origin/d mainly as vegetables or fruits. Of the participants, 14% had high serum LDL cholesterol concentrations, 46% had low serum HDL cholesterol, and none had high triglycerides. Of raw food consumers, 38% were vitamin B-12 deficient, whereas 12% had an increased mean corpuscular volume (MCV). Plasma tHcy concentrations were correlated with plasma vitamin B-12 concentrations (r = -0.450, P < 0.001), but not with plasma folate. Plasma tHcy and IVICV concentrations were higher in those in the lowest quintile of consumption of food of animal origin (P-trend < 0.001). This study indicates that consumption of a strict raw food diet lowers plasma total cholesterol and triglyceride concentrations, but also lowers serum HDL cholesterol and increases tHcy concentrations due to vitamin B-12 deficiency.



Zitierstile

Harvard-ZitierstilKoebnick, C., Garcia, A., Dagnelie, P., Strassner, C., Lindemans, J., Katz, N., et al. (2005) Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans, The Journal of Nutrition, 135(10), pp. 2372-2378. https://doi.org/10.1093/jn/135.10.2372

APA-ZitierstilKoebnick, C., Garcia, A., Dagnelie, P., Strassner, C., Lindemans, J., Katz, N., Leitzmann, C., & Hoffmann, I. (2005). Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans. The Journal of Nutrition. 135(10), 2372-2378. https://doi.org/10.1093/jn/135.10.2372



Schlagwörter


ANTIOXIDANT STATUSCOLLABORATIVE ANALYSISHEART-DISEASEIMPAIRS ENDOTHELIAL FUNCTIONraw food dietVEGAN DIETVEGETABLE INTAKEVEGETARIAN DIETvegetarian dietsVitamin B-12VITAMIN-B-12 STATUS

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