Journalartikel

Jahr der Veröffentlichung: 2004

Seiten: 931-935

Zeitschrift: Archives of Oral Biology

Bandnummer: 49

Heftnummer: 11

ISSN: 0003-9969

DOI Link: https://doi.org/10.1016/j.archoralbio.2004.05.010

Verlag: Elsevier

Abstract: 

After an initial demineralisation, an intensive fluoridation is capable of inhibiting the erosive mineral loss in dentine completely, which might be related to the presence of the exposed organic dentine matrix. Aim of the present study was, therefore, to evaluate whether fluoride is also effective when the organic material is removed.

The study was a cyclic de- and remineratisation model over 5 days in vitro. Samples from human coronal dentine were demineralised with citric acid (pH 2.3; 6 x 10 min per day) and intermittently stored in a remineratisation solution. Groups (n = 25 each) were defined as follows: Group 1: erosion only, no fluoridation; Group 2: erosion, alternately fluoridation with toothpaste (NaF; 0.15% F-; 3 x 5 min per day), mouthrinse (Olaflur/SnF2; 0.025 F-; 3 x 5 min per day) and get (Olaflur/NaF; 1.25% F-; at Days 1 and 3 instead of one toothpaste application); Group 3: erosion and fluoridation as Group 2, organic material was continuously removed with collagenase (from Clostridium Histolyticum type VII, 100 U/ml) added to the remineralisation solution. Mineral content was monitored daily using longitudinal microradiogaphy.

After fluoridation in the presence of collagenase, a linear increase in mineral. toss (73.3 +/- 17.6 mum at Day 5) was observed, which significantly (P less than or equal to 0.001) exceeded that of the control group (45.9 +/- 14.3 mum at Day 5). After fluoridation in the absence of collagenase, mineral. toss ceased after the 2nd day (12.2 +/- 10.2 mum at Day 5) and was significantly tower compared to Groups 1 and 3 (P less than or equal to 0.001).

The results indicate that the dentine matrix is essential for the effectiveness of fluoride in dental. erosion. (C) 2004 Elsevier Ltd. All rights reserved.

Harvard-Zitierstil: Ganss, C., Klimek, J. and Starck, C. (2004) Quantitative analysis of the impact of the organic matrix on the fluoride effect on erosion progression in human dentine using longitudinal microradiography, Archives of oral biology, 49(11), pp. 931-935. https://doi.org/10.1016/j.archoralbio.2004.05.010

APA-Zitierstil: Ganss, C., Klimek, J., & Starck, C. (2004). Quantitative analysis of the impact of the organic matrix on the fluoride effect on erosion progression in human dentine using longitudinal microradiography. Archives of oral biology. 49(11), 931-935. https://doi.org/10.1016/j.archoralbio.2004.05.010