Journal article

Global carbon/nitrogen control by PII signal transduction in cyanobacteria:: from signals to targets


Authors listForchhammer, K

Publication year2004

Pages319-333

JournalFEMS Microbiology Reviews

Volume number28

Issue number3

ISSN0168-6445

eISSN1574-6976

Open access statusBronze

DOI Linkhttps://doi.org/10.1016/j.femsre.2003.11.001

PublisherOxford University Press


Abstract
P-II signal transduction plays a pervasive role in microbial nitrogen control. Different phylogenetic lineages have developed various signal transduction schemes around the highly conserved core of the signalling system, which consists of the P-II proteins. Among all various bacterial PI, signalling systems, the one in cyanobacteria is so far unique: in unicellular strains, the mode of covalent modification is by serine phosphorylation and the interpretation of the cellular nitrogen status occurs by measuring the 2-oxoglutarate levels. Recent advances have been the identification of the phospho-P-II phosphatase, the resolution of the crystal structure of PI, proteins from Synechococcus and Synechocystis strains and the identification of novel functions of P-II regulation in cyanobacteria, which highlight the central role of P-II signalling for the acclimation to changing carbon-nitrogen regimes. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.



Citation Styles

Harvard Citation styleForchhammer, K. (2004) Global carbon/nitrogen control by PII signal transduction in cyanobacteria:: from signals to targets, FEMS Microbiology Reviews, 28(3), pp. 319-333. https://doi.org/10.1016/j.femsre.2003.11.001

APA Citation styleForchhammer, K. (2004). Global carbon/nitrogen control by PII signal transduction in cyanobacteria:: from signals to targets. FEMS Microbiology Reviews. 28(3), 319-333. https://doi.org/10.1016/j.femsre.2003.11.001



Keywords


2-oxoglutarateCOLI GLUTAMINE-SYNTHETASEGlnBGLNB GENE-PRODUCTnitrate transportnitrogen regulationNITROGEN REGULATOR NTCANtcAPCC 7942PHOTOSYNTHETIC ELECTRON-TRANSPORTPII PROTEINPROTEIN PHOSPHATASEprotein phosphorylationSP STRAIN PCC-7942SYNECHOCOCCUS-SP PCC-7942

Last updated on 2025-10-06 at 09:31