Journal article
Authors list: Forchhammer, K
Publication year: 2004
Pages: 319-333
Journal: FEMS Microbiology Reviews
Volume number: 28
Issue number: 3
ISSN: 0168-6445
eISSN: 1574-6976
Open access status: Bronze
DOI Link: https://doi.org/10.1016/j.femsre.2003.11.001
Publisher: Oxford University Press
Abstract:
P-II signal transduction plays a pervasive role in microbial nitrogen control. Different phylogenetic lineages have developed various signal transduction schemes around the highly conserved core of the signalling system, which consists of the P-II proteins. Among all various bacterial PI, signalling systems, the one in cyanobacteria is so far unique: in unicellular strains, the mode of covalent modification is by serine phosphorylation and the interpretation of the cellular nitrogen status occurs by measuring the 2-oxoglutarate levels. Recent advances have been the identification of the phospho-P-II phosphatase, the resolution of the crystal structure of PI, proteins from Synechococcus and Synechocystis strains and the identification of novel functions of P-II regulation in cyanobacteria, which highlight the central role of P-II signalling for the acclimation to changing carbon-nitrogen regimes. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Citation Styles
Harvard Citation style: Forchhammer, K. (2004) Global carbon/nitrogen control by PII signal transduction in cyanobacteria:: from signals to targets, FEMS Microbiology Reviews, 28(3), pp. 319-333. https://doi.org/10.1016/j.femsre.2003.11.001
APA Citation style: Forchhammer, K. (2004). Global carbon/nitrogen control by PII signal transduction in cyanobacteria:: from signals to targets. FEMS Microbiology Reviews. 28(3), 319-333. https://doi.org/10.1016/j.femsre.2003.11.001
Keywords
2-oxoglutarate; COLI GLUTAMINE-SYNTHETASE; GlnB; GLNB GENE-PRODUCT; nitrate transport; nitrogen regulation; NITROGEN REGULATOR NTCA; NtcA; PCC 7942; PHOTOSYNTHETIC ELECTRON-TRANSPORT; PII PROTEIN; PROTEIN PHOSPHATASE; protein phosphorylation; SP STRAIN PCC-7942; SYNECHOCOCCUS-SP PCC-7942