Journal article

Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders


Authors listOmwandho, COA; Gruessner, SEM; Roberts, TK; Tinneberg, HR

Publication year2004

Pages359-370

JournalClinical Chemistry and Laboratory Medicine

Volume number42

Issue number4

ISSN1434-6621

eISSN1437-4331

DOI Linkhttps://doi.org/10.1515/CCLM.2004.065

PublisherDe Gruyter


Abstract
Recurrent pregnancy loss has been associated with autoimmune responses to membrane phospholipids and alloimmune reactions against paternally derived molecules on the trophoblast. The problem is psychologically and economically stressful as it undermines the capacity of some couples to reproduce and participate effectively in the daytoday economic activities. This article reviews the adoption of intravenous immunoglobulin as a form of therapy for the clinical management of recurrent pregnancy loss and of selected autoimmune disorders. Side effects, contraindications and safety of use are discussed.



Citation Styles

Harvard Citation styleOmwandho, C., Gruessner, S., Roberts, T. and Tinneberg, H. (2004) Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders, Clinical Chemistry and Laboratory Medicine, 42(4), pp. 359-370. https://doi.org/10.1515/CCLM.2004.065

APA Citation styleOmwandho, C., Gruessner, S., Roberts, T., & Tinneberg, H. (2004). Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders. Clinical Chemistry and Laboratory Medicine. 42(4), 359-370. https://doi.org/10.1515/CCLM.2004.065



Keywords


autoimmune disordersGAMMA-GLOBULINGUILLAIN-BARRE-SYNDROMEIMMUNE GLOBULININTRAVENOUS IMMUNOGLOBULINKAWASAKI-DISEASELUPUS NEPHRITISORAL PREDNISONEPLASMA-EXCHANGEPOSSIBLE MECHANISMRANDOMIZED-TRIALrecurrent pregnancy loss

Last updated on 2025-02-04 at 07:50