Conference paper

Publication year: 2003

Pages: 293-299

Journal: European Urology

Volume number: 43

Issue number: 3

ISSN: 0302-2838

eISSN: 1873-7560

DOI Link: https://doi.org/10.1016/S0302-2838(03)00003-4

Conference: 16th Congress of the European-Association-of-Eurology (EAU)

Publisher: Elsevier

Abstract: 

Objective: To compare the value of magnetic resonance imaging (MRI) with palpation and ultrasound in the evaluation of plaque formation in Peyronie's disease.

Methods: 57 patients underwent a standardized diagnostic procedure to evaluate plaque formation consisting of palpation and ultrasonography (7.5 MHz). MRI was performed during flaccidity and during erection induced by Prostaglandin El including intravenous application of Gadolinium-diethylenetriaminepentaacetic acid (Gd-DPTA).

Results: With all methods, 93 plaques have been detected in 57 patients. 85 plaques (91.4%) have been evaluated by palpation alone. Using ultrasound, 52 of these 93 plaques (55.9%) were detectable. This is equivalent to 61.1% of the palpable plaques. MRI confirmed 58 of the palpated plaques (68.2%) and exposed 8 primarily not palpable plaques at the penile basis. MRI revealed more palpable plaques than ultrasound, but this finding was not significant (p = 0.083). By means of sonography, calcification was evident in 14 plaques. MRI failed in revealing any calcification. After application of Gd-DPTA, 5 of 57 patients (9%) demonstrated contrast enhancement indicating local inflammation. None of these patients reported on penile pain.

Conclusions: Penile palpation in combination with ultrasound represents the method of choice to diagnose plaque formation in Peyronie's disease. MRI provides better information on plaque formation at the penile basis. Calcification can only be proven by ultrasound, not by MRI. There may be additional information by MRI about local inflammation. A prospective study comparing the histological and MRI findings should be performed to answer the question, if pain is really associated with inflammation. (C) 2003 Elsevier Science B.V. All rights reserved.

Harvard Citation style: Hauck, E., Hackstein, N., Vosshenrich, R., Diemer, T., Schmelz, H., Bschleipfer, T., et al. (2003) Diagnostic value of magnetic resonance Imaging in Peyronie's disease - A comparison both with palpation and ultrasound in the evaluation of plaque formation, European Urology, 43(3), pp. 293-299. https://doi.org/10.1016/S0302-2838(03)00003-4

APA Citation style: Hauck, E., Hackstein, N., Vosshenrich, R., Diemer, T., Schmelz, H., Bschleipfer, T., Schroeder-Printzen, I., & Weidner, W. (2003). Diagnostic value of magnetic resonance Imaging in Peyronie's disease - A comparison both with palpation and ultrasound in the evaluation of plaque formation. European Urology. 43(3), 293-299. https://doi.org/10.1016/S0302-2838(03)00003-4