Journal article

Publication year: 2002

Pages: 30-33

Journal: Pancreatology

Volume number: 2

Issue number: 1

ISSN: 1424-3903

DOI Link: https://doi.org/10.1159/000049445

Publisher: Elsevier

Abstract: 
Background: Pancreatic exocrine dysfunction has been described frequently in IDDM and NIDDM patients. Most authors tried to explain this finding as a diabetic complication. On the other hand, diabetes secondary to chronic pancreatitis (CP) might be more common than believed so far. Aim of the Study: In this study we evaluated pancreatograms of patients with known diabetes mellitus in order to detect ductal morphology changes characteristic for CP. Methods: Consecutive diabetic patients admitted for ERCP for different reasons were evaluated retrospectively concerning ERCP findings, especially pancreatic duct changes (Cambridge classification), diabetes type, duration and therapy. Results: 156 patients (76 male, 80 female; mean age 60 years (19-93)) were studied (38 IDDM; 118 NIDDM). Pancreatic ducts were classified as normal in 23.3%, CPdegreesI in 22.7%, CPdegreesII in 32.7% and CPdegreesIII in 21.3%. The duct changes did not correlate with diabetes type (p = 0.19), diabetes duration (p=0.38), diabetes therapy (p = 0.5) or age (p = 0.48). Conclusion: Since CP should be defined by morphological and functional changes, it must be concluded that a substantial number of patients with a primary diagnosis of diabetes mellitus may have CP as a concomitant disease or, more likely, as a cause for their diabetic state. Copyright (C) 2002 S. Karger AG, Basel and IAP.

Harvard Citation style: Hardt, P., Killinger, A., Nalop, J., Schnell-Kretschmer, H., Zekorn, T. and Klör, H. (2002) Chronic pancreatitis and diabetes mellitus -: A retrospective analysis of 156 ERCP investigations in patients with insulin-dependent and non-insulin-dependent diabetes mellitus, Pancreatology, 2(1), pp. 30-33. https://doi.org/10.1159/000049445

APA Citation style: Hardt, P., Killinger, A., Nalop, J., Schnell-Kretschmer, H., Zekorn, T., & Klör, H. (2002). Chronic pancreatitis and diabetes mellitus -: A retrospective analysis of 156 ERCP investigations in patients with insulin-dependent and non-insulin-dependent diabetes mellitus. Pancreatology. 2(1), 30-33. https://doi.org/10.1159/000049445