Journal article

Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers


Authors listWeiss, S; Chakraborty, T

Publication year2001

Pages467-472

JournalCurrent Opinion in Biotechnology

Volume number12

Issue number5

ISSN0958-1669

eISSN1879-0429

DOI Linkhttps://doi.org/10.1016/S0958-1669(00)00247-0

PublisherElsevier


Abstract
The concept of transkingom transfer of DNA from bacteria to other organisms has recently been extended to include eukaryotic host cells. Intracellular bacteria have been shown to transfer eukaryotic expression plasmids to mammalian host cells in vitro and in vivo. This can be used to induce immune responses towards protein antigens encoded by the plasmid, to complement genetic defects or even to direct the production of proteins in appropriate organs. The ease of generating such vehicles makes this a highly attractive area for further research.



Citation Styles

Harvard Citation styleWeiss, S. and Chakraborty, T. (2001) Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers, Current Opinion in Biotechnology, 12(5), pp. 467-472. https://doi.org/10.1016/S0958-1669(00)00247-0

APA Citation styleWeiss, S., & Chakraborty, T. (2001). Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers. Current Opinion in Biotechnology. 12(5), 467-472. https://doi.org/10.1016/S0958-1669(00)00247-0



Keywords


ATTENUATED SALMONELLA-TYPHIMURIUMDELIVERY VEHICLEDNA-MEDIATED IMMUNIZATIONGENE-TRANSFERLISTERIA-MONOCYTOGENESPROTECTIVE IMMUNITYSHIGELLA

Last updated on 2025-02-04 at 07:35