Journal article

Publication year: 2001

Pages: 79-89

Journal: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie

Volume number: 36

Issue number: 2

ISSN: 0939-2661

DOI Link: https://doi.org/10.1055/s-2001-11057

Publisher: Georg Thieme Verlag

Abstract: 
The transmissible spongiform encephalopathies (TSE) are known to affect humans and various animals. The bovine spongiform encephalopathy (BSE) and the human Creutzfeldt-Jacob disease (CID) are among the most notable degenerative disorders caused by prions. Considering the BSE epidemic and the description of a new variant of Creutzfeldt-Jacob disease (nvCJD), which is probably related to bovine spongiform encephalopathy, TSE have recently gained a lot of public attention. Although the causative factors (prions, viruses) are still under discussion, none of the present concepts are explanatory for all aspects of the human CJD. CJD may present as a sporadic, genetic, or infectious illness and there is now considerable concern that bovine prions may have been passed to humans. To exclude transmission of CJD via medical products and instruments, the effectiveness of cleaning, disinfection and sterilization procedures must be firmly established. This manuscript presents an overview to anaesthesiology and intensive care medicine of recommended inactivation procedures and assessed these procedures in the light of the inactivation of prions.

Harvard Citation style: Menges, T., Langefeld, T., Krumholz, W. and Hempelmann, G. (2001) Transmissible spongiform encephalopathies - Anesthesiological and intensive care management, Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie, 36(2), pp. 79-89. https://doi.org/10.1055/s-2001-11057

APA Citation style: Menges, T., Langefeld, T., Krumholz, W., & Hempelmann, G. (2001). Transmissible spongiform encephalopathies - Anesthesiological and intensive care management. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie. 36(2), 79-89. https://doi.org/10.1055/s-2001-11057