Journal article

Publication year: 2001

Pages: 15-24

Journal: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie

Volume number: 36

Issue number: 1

ISSN: 0939-2661

DOI Link: https://doi.org/10.1055/s-2001-10236

Publisher: Georg Thieme Verlag

Abstract: 
Prion Diseases. Transmissible spongiform encephalopathies (TSEs) are clinical entities recognized both in humans and animals. Current evidence suggests that TSEs are caused by a self-propagating alteration of infectious protein particles known as prions, In addition, there is strong evidence for a genetic predisposition for the disease and documentation that transmission can cross species borders, The current public awareness of TSEs has resulted from the clinical symptoms observed in bovine spongiform encephalopathy (BSE) and the demonstration that a new Variant of the Creutzfeld-Jacobs syndrome is probably the result of transmission from animals to humans. This has led to uncertainity amongst clinical personnel when dealing with patients presenting with TSEs, We review briefly the spectrum of TSEs known both in animals and humans, report on recent developments in the diagnostics and therapy, and discuss iatrogenic sources of infection.

Harvard Citation style: Hossain, H. and Chakraborty, T. (2001) Prion diseases., Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie, 36(1), pp. 15-24. https://doi.org/10.1055/s-2001-10236

APA Citation style: Hossain, H., & Chakraborty, T. (2001). Prion diseases.. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie. 36(1), 15-24. https://doi.org/10.1055/s-2001-10236