Journal article

Skin, psyche, immune system: A vector-time series model


Authors listBrosig, B; Brähler, E

Publication year2001

Pages279-296

JournalZeitschrift für klinische Psychologie, Psychiatrie und Psychotherapie

Volume number49

Issue number3

ISSN0723-6557

PublisherSchöningh


Abstract

Time-series models were used increasingly for the analysis of complex interacting systems in psychological and social sciences research. Taking atopic dermatitis as a psychosomatic disease model, the interaction of moods (depression, activation and aggression) psychoneuroimmunological standard parameter such as salivary cortisol and secretory IgA (sIgA) and skin complaints is studied by vector auto regression (VAR)- und vector error correction (VEC)-models. Using a standardized diary technique, moods and skin symptoms were documented and saliva samples were secured. In addition, setting factors and the rhythm of the week were noted.

It could be shown by a VAR-model that the severity of skin symptomatology was predicted by a decrease of sIgA. If the skin was already affected, this was followed by a deactivated mood. Skin symptoms were also influenced by setting factors (family therapy and temporary discontinuation of the therapy). sIgA was modulated (VEC-model) by depressive, de-activated moods and psychosocial influences (weekend). Cortisol in saliva was increased by a family therapy session.

VAR- and VEC-models, therefore, may be used successfully in multivariate time-series models under control of autocorrelative processes. In addition, they enable the analysis of feed back circles in a bio-psycho-somatic process.




Citation Styles

Harvard Citation styleBrosig, B. and Brähler, E. (2001) Skin, psyche, immune system: A vector-time series model, Zeitschrift für klinische Psychologie, Psychiatrie und Psychotherapie, 49(3), pp. 279-296

APA Citation styleBrosig, B., & Brähler, E. (2001). Skin, psyche, immune system: A vector-time series model. Zeitschrift für klinische Psychologie, Psychiatrie und Psychotherapie. 49(3), 279-296.



Keywords


ATOPIC-DERMATITISIGASALIVARY IMMUNOGLOBULINurticaria

Last updated on 2025-21-05 at 18:45