Journal article

Publication year: 1995

Pages: 676-680

Journal: Deutsche Medizinische Wochenschrift

Volume number: 120

Issue number: 19

ISSN: 0012-0472

DOI Link: https://doi.org/10.1055/s-2008-1055395

Publisher: Georg Thieme Verlag

Abstract: 
Over a period of several months a 33-year-old man had recurrent pulmonary emboli. No thromboses could be demonstrated in the peripheral venous system. Transoesophageal echocardiography showed two spherical space-occupying structures in the right ventricle which were removed operatively under the suspected diagnosis of multilobular myxomas. However, their histological examination revealed pure thrombi that had grown by apposition. This unusual findings of right-ventricular thrombi could not be explained pre- and intraoperatively by any local thrombi-favouring changes in the right heart. Tests of clotting mechanisms demonstrated lupus anticoagulans (kaolin-clotting-time mixture test: LA index 21.7 [normal: <15]), as well as an increased IgG cardiolipin antibody concentration of 19.3 U/l). As no underlying disease was discovered, the diagnosis was by definition primary antiphospholipid syndrome. No further thrombo-embolism has occurred during continuing oral anticoagulation with phenprocoumon.

Harvard Citation style: BRAUNINGER, S., WINCKELMANN, G., BOHLE, R., BAUER, E., STELLWAAG, M. and LAMBERTZ, H. (1995) RIGHT-VENTRICULAR THROMBI IN PRIMARY ANTIPHOSPHOLIPID SYNDROME, Deutsche Medizinische Wochenschrift, 120(19), pp. 676-680. https://doi.org/10.1055/s-2008-1055395

APA Citation style: BRAUNINGER, S., WINCKELMANN, G., BOHLE, R., BAUER, E., STELLWAAG, M., & LAMBERTZ, H. (1995). RIGHT-VENTRICULAR THROMBI IN PRIMARY ANTIPHOSPHOLIPID SYNDROME. Deutsche Medizinische Wochenschrift. 120(19), 676-680. https://doi.org/10.1055/s-2008-1055395