Journal article

ENTEROSTATIN INHIBITS INSULIN-SECRETION FROM ISOLATED PERIFUSED RAT ISLETS


Authors listERLANSONALBERTSSON, C; HERING, B; BRETZEL, RG; FEDERLIN, K

Publication year1994

Pages160-163

JournalActa Diabetologica

Volume number31

Issue number3

ISSN0940-5429

DOI Linkhttps://doi.org/10.1007/BF00570372

PublisherSpringer


Abstract
The effect of enterostatin on glucose-induced insulin secretion was examined in isolated, perifused rat islets. In the presence of 16.67 mM glucose, there was significant inhibition of insulin secretion at concentrations of 200 nM, 2, 20 and 40 mu M enterostatin. In particular, the second phase of insulin secretion was inhibited. With a low concentration of glucose (2.78 mM), there was no significant effect on insulin secretion by enterostatin. The inhibition of insulin secretion exerted by enterostatin may be an important effect in the prevention of insulin resistance.



Citation Styles

Harvard Citation styleERLANSONALBERTSSON, C., HERING, B., BRETZEL, R. and FEDERLIN, K. (1994) ENTEROSTATIN INHIBITS INSULIN-SECRETION FROM ISOLATED PERIFUSED RAT ISLETS, Acta Diabetologica, 31(3), pp. 160-163. https://doi.org/10.1007/BF00570372

APA Citation styleERLANSONALBERTSSON, C., HERING, B., BRETZEL, R., & FEDERLIN, K. (1994). ENTEROSTATIN INHIBITS INSULIN-SECRETION FROM ISOLATED PERIFUSED RAT ISLETS. Acta Diabetologica. 31(3), 160-163. https://doi.org/10.1007/BF00570372



Keywords


ACTIVATION PEPTIDECOLIPASEFAT INTAKEFOOD-INTAKEINJECTIONINVITROPANCREATIC PROCOLIPASEPROCOLIPASE PROPEPTIDE

Last updated on 2025-02-04 at 07:01