Journalartikel

INTRAVENOUS OR ORAL I-131 TREATMENT OF THYROTOXICOSIS AND THYROID-CANCER


AutorenlisteMULLER, KD; GREBE, SF; BOCK, FL; MULLER, H; FANGEWISCH, GL

Jahr der Veröffentlichung1994

Seiten87-92

ZeitschriftNuclear Medicine

Bandnummer33

Heftnummer3

ISSN0029-5566

VerlagSchattauer


Abstract
The purpose of this study was to determine differences in I-131 biokinetics after oral or intravenous treatment of hyperthyroidism (0,81 GBq) or differentiated thyroid cancer (1,85 GBq) following thyroidectomy. 20 patients with differentiated carcinoma and 20 patients with hyperthyroidism were studied. In each group 10 patients were treated perorally and 10 patients intravenously. The integrated whole-body activities during therapy were significantly lower, by an average 23% (cancer) and 45% (hyperthyroidism) than after oral application. It is most likely that these differences between oral and intravenous application are due to the higher serum activity after intravenous therapy. It is concluded that a higher activity dose of I-131 must be given orally to achieve the same target dose as after intravenous application.



Zitierstile

Harvard-ZitierstilMULLER, K., GREBE, S., BOCK, F., MULLER, H. and FANGEWISCH, G. (1994) INTRAVENOUS OR ORAL I-131 TREATMENT OF THYROTOXICOSIS AND THYROID-CANCER, Nuclear Medicine, 33(3), pp. 87-92

APA-ZitierstilMULLER, K., GREBE, S., BOCK, F., MULLER, H., & FANGEWISCH, G. (1994). INTRAVENOUS OR ORAL I-131 TREATMENT OF THYROTOXICOSIS AND THYROID-CANCER. Nuclear Medicine. 33(3), 87-92.



Schlagwörter


BIOKINETICSDOSE CALCULATIONI-131RADIOIODINE THERAPYThyroid

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