Journalartikel

HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS


AutorenlisteROMPEL, R; WEIDNER, W; MUELLERECKHARDT, G

Jahr der Veröffentlichung1991

Seiten104-106

ZeitschriftTissue Antigens

Bandnummer38

Heftnummer3

ISSN0001-2815

eISSN1399-0039

DOI Linkhttps://doi.org/10.1111/j.1399-0039.1991.tb02021.x

VerlagWiley: 12 months


Abstract
HLA typing for class I and class II antigens was done in 52 unrelated patients suffering from idiopathic Peyronie's disease. The controversially discussed association with the HLA-B7 cross-reacting group could not be confirmed. Marked deviations of antigen frequencies were observed for HLA-A1, B8, Cw7, DR3 and DQw2 compared to healthy local controls. After correction of p-values, A1 (p(c) < 0.05) and DQw2 (p(c) < 0.01) remained significant. A possible association of Peyronie's disease with markers of the HLA-A1, B8, Cw7, DR3, DQw2 haplotype, as first described here, would suggest autoimmunological factors in this disorder of otherwise unknown etiopathogenesis.



Zitierstile

Harvard-ZitierstilROMPEL, R., WEIDNER, W. and MUELLERECKHARDT, G. (1991) HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS, Tissue Antigens, 38(3), pp. 104-106. https://doi.org/10.1111/j.1399-0039.1991.tb02021.x

APA-ZitierstilROMPEL, R., WEIDNER, W., & MUELLERECKHARDT, G. (1991). HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS. Tissue Antigens. 38(3), 104-106. https://doi.org/10.1111/j.1399-0039.1991.tb02021.x



Schlagwörter


ANTIGENSCLASS-IIHLA AND DISEASEHLA ANTIGENSPEYRONIES DISEASE

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