Journalartikel

Jahr der Veröffentlichung: 1990

Seiten: 747-751

Zeitschrift: Journal of veterinary medicine. Series A: Physiology, pathology, clinical medicine

Bandnummer: 37

Heftnummer: 10

ISSN: 0931-184X

DOI Link: https://doi.org/10.1111/j.1439-0442.1990.tb00968.x

Verlag: Blackwell Verlag

Abstract: 
The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope does in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 X 0.8 mCi (29.6 MBq) or 1 X 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400 000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.

Harvard-Zitierstil: HANAUER, G. and SCHROTH, H. (1990) ESTIMATION OF THE RADIOIODINE DOSE NECESSARY FOR COMPLETE ABLATION OF THE THYROID-GLAND IN MALE WISTAR RATS, Journal of veterinary medicine. Series A, Physiology, pathology, clinical medicine, 37(10), pp. 747-751. https://doi.org/10.1111/j.1439-0442.1990.tb00968.x

APA-Zitierstil: HANAUER, G., & SCHROTH, H. (1990). ESTIMATION OF THE RADIOIODINE DOSE NECESSARY FOR COMPLETE ABLATION OF THE THYROID-GLAND IN MALE WISTAR RATS. Journal of veterinary medicine. Series A, Physiology, pathology, clinical medicine. 37(10), 747-751. https://doi.org/10.1111/j.1439-0442.1990.tb00968.x