Journalartikel
Autorenliste: MUELLERECKHARDT, C; KIEFEL, V; GRUBERT, A; KROLL, H; WEISHEIT, M; SCHMIDT, S; MUELLERECKHARDT, G; SANTOSO, S
Jahr der Veröffentlichung: 1989
Seiten: 363-366
Zeitschrift: The Lancet
Bandnummer: 1
Heftnummer: 8634
ISSN: 0140-6736
eISSN: 1474-547X
Verlag: Elsevier
Abstract:
Serological and clinical data were collected in 348 cases of suspected neonatal alloimmune thrombocytopenia (NAT). Of the 144 mothers who were Zwa-negative, 107 had Zwa antibodies.sbd.alone (94); with HLA antibodies (12); or with Bra antibodies (1). Antibodies were detected in 12 of the 204 Zwa-positive mothers as follows: anti-Bra (9), anti-Zwb (1), anti-Baka with HLA antibody (1), and blood group B isoagglutinins (1). The frequency of NAT due to Bra incompatibility (19%) was second to Zwa (78%). Zwa-NAT was clinically the most severe (14% had intracranial haemorrhages) and responded well to either maternal platelet transfusions or intravenous IgG. In Bra-NAT intracranial haemorrhages were not observed and most children recovered without specific therapy.
Zitierstile
Harvard-Zitierstil: MUELLERECKHARDT, C., KIEFEL, V., GRUBERT, A., KROLL, H., WEISHEIT, M., SCHMIDT, S., et al. (1989) 348 CASES OF SUSPECTED NEONATAL ALLOIMMUNE THROMBOCYTOPENIA, The Lancet, 1(8634), pp. 363-366
APA-Zitierstil: MUELLERECKHARDT, C., KIEFEL, V., GRUBERT, A., KROLL, H., WEISHEIT, M., SCHMIDT, S., MUELLERECKHARDT, G., & SANTOSO, S. (1989). 348 CASES OF SUSPECTED NEONATAL ALLOIMMUNE THROMBOCYTOPENIA. The Lancet. 1(8634), 363-366.
