DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES - Forschungsportal der Justus-Liebig-Universität Gießen:

Journalartikel

DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES

Autorenliste: RACKWITZ, HR; ROHDE, W; SANGER, HL

Jahr der Veröffentlichung: 1981

Seiten: 297-301

Zeitschrift: Nature

Bandnummer: 291

Heftnummer: 5813

ISSN: 0028-0836

eISSN: 1476-4687

DOI Link: https://doi.org/10.1038/291297a0

Verlag: Nature Research

Abstract:
DNA-dependent RNA polymerase II purified from healthy plant [tomato, wheat germ] tissue is capable of synthesizing linear (-)-viroid RNA copies of full length from (+)-viroid RNA templates in vitro. Together with the specific .alpha.-amanitin sensitivity of viroid replication observed in vivo, these findings suggest that viroids replicate by an entirely novel mechanism in which infecting viroid RNA molecules are copied by the host enzyme, which is normally responsible for the synthesis of nuclear precursors to messenger RNA.

Zitierstile

Harvard-Zitierstil: RACKWITZ, H., ROHDE, W. and SANGER, H. (1981) DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES, Nature, 291(5813), pp. 297-301. https://doi.org/10.1038/291297a0

APA-Zitierstil: RACKWITZ, H., ROHDE, W., & SANGER, H. (1981). DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES. Nature. 291(5813), 297-301. https://doi.org/10.1038/291297a0

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