Journal article

MORPHOLOGICAL-CHANGES IN ULTRASTRUCTURE OF THYROID EPITHELIUM OF NOTOPHTHALMUS-VIRIDESCENS AFTER HYPOPHYSECTOMY AND TSH-STIMULATION AND PROLACTIN STIMULATION


Authors listKRACHT, J; WEBER, EG

Publication year1978

Pages305-313

JournalCell and Tissue Research

Volume number187

Issue number2

ISSN0302-766X

eISSN1432-0878

PublisherSpringer


Abstract
In the newt, N. viridescens, hypophysectomy resulted in progressive atrophy of the thyroid cells to the point of irreversible degeneration. After exclusive TSH[thyroid stimulating hormone]-stimulation of hypophysectomized newts, the endocytotic activity of the follicular epithelium increased. Prolactin [PRL] stimulation under the same conditions prevented atrophy but did not result in increased cell activity, as expressed by the reduced amount of microvilli and the lack of endocytotic activity. Combined TSH- and PRL stimulation also resulted in cell activation, but the activation level of exclusively TSH-stimulated cells was not reached. Although PRL prevents cellular atrophy and degeneration of the follicular epithelium, it reduces the TSH-induced activation of the thyroid epithelium.



Citation Styles

Harvard Citation styleKRACHT, J. and WEBER, E. (1978) MORPHOLOGICAL-CHANGES IN ULTRASTRUCTURE OF THYROID EPITHELIUM OF NOTOPHTHALMUS-VIRIDESCENS AFTER HYPOPHYSECTOMY AND TSH-STIMULATION AND PROLACTIN STIMULATION, Cell and Tissue Research, 187(2), pp. 305-313

APA Citation styleKRACHT, J., & WEBER, E. (1978). MORPHOLOGICAL-CHANGES IN ULTRASTRUCTURE OF THYROID EPITHELIUM OF NOTOPHTHALMUS-VIRIDESCENS AFTER HYPOPHYSECTOMY AND TSH-STIMULATION AND PROLACTIN STIMULATION. Cell and Tissue Research. 187(2), 305-313.



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