Journalartikel

Jahr der Veröffentlichung: 1973

Seiten: 1-10

Zeitschrift: Virchows Archiv. A: Pathological anatomy and histopathology

Bandnummer: 361

Heftnummer: 1

ISSN: 0042-6423

DOI Link: https://doi.org/10.1007/BF00543545

Verlag: Springer

Abstract: 

The material obtained from 11 cases of gliosis and 4 cases of tumours associated with Rosenthal fibres was studied under optical and electron microscope.
Ultrastructurally the Rosenthal fibres appear in the form of osmiophil amorphous masses deposited in the cellular cytoplasm among the glial filaments, the latter showing no degenerative phenomena.
The development of Rosenthal fibre-forming gliosis is closely linked to dysplastic processes, resulting in discontinuity of the ependymal epithelium, concomitantly affecting the normal embryonic development of the subependymal glial system.
The spongioblast, a Rosenthal fibre-forming element, represents the type of dysplastic, subependymal glial cell with fibrillofoming and proliferative potentiallites (Bielschowsky, Hallervorden, Schlote). The presence of osmiophil bodies next to Rosenthal fibres forms the specific ultrastructural properties of the spongioblastic cell in contrast to the situation in normally differentiated astrocyte.

Harvard-Zitierstil: Vuia, O. (1973) Dysplastic gliosis (spongioblastosis) and the rosenthal fibres. Pathogenetic contributions, Virchows Archiv. A: Pathological anatomy and histopathology, 361(1), pp. 1-10. https://doi.org/10.1007/BF00543545

APA-Zitierstil: Vuia, O. (1973). Dysplastic gliosis (spongioblastosis) and the rosenthal fibres. Pathogenetic contributions. Virchows Archiv. A: Pathological anatomy and histopathology. 361(1), 1-10. https://doi.org/10.1007/BF00543545