Journal article

Publication year: 2019

Pages: 118-128

Journal: Environmental Microbiology Reports

Volume number: 11

Issue number: 2

ISSN: 1758-2229

DOI Link: https://doi.org/10.1111/1758-2229.12718

Publisher: Wiley

Abstract: 
As a free-living bacterium Rhodobacter sphaeroides needs to respond to many environmental stresses. Oxidative stress, membrane stress or heat stress induce the ompR-1 gene encoding a protein of the OmpR family. Overexpression of OmpR-1 results in increased resistance to organic peroxides and diamide. Our data demonstrate that OmpR-1 positively affects expression of several sRNAs with an established role in R. sphaeroides stress defences and negatively affects the promoter of the rpoHI gene. The RpoHI sigma factor has a main role in the activation of many stress responses. Thus OmpR-1 has a balancing effect on the activation of the RpoHI regulon. We present a model with OmpR-1 as part of a regulatory network controlling stress defences in R. sphaeroides.

Harvard Citation style: Zhao, Z., Peng, T., Oh, J., Glaeser, J., Weber, L., Li, Q., et al. (2019) A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides, Environmental Microbiology Reports, 11(2), pp. 118-128. https://doi.org/10.1111/1758-2229.12718

APA Citation style: Zhao, Z., Peng, T., Oh, J., Glaeser, J., Weber, L., Li, Q., & Klug, G. (2019). A response regulator of the OmpR family is part of the regulatory network controlling the oxidative stress response of Rhodobacter sphaeroides. Environmental Microbiology Reports. 11(2), 118-128. https://doi.org/10.1111/1758-2229.12718