Journalartikel

Jahr der Veröffentlichung: 1994

Seiten: 462-464

Zeitschrift: Pflügers Archiv European Journal of Physiology

Bandnummer: 426

Heftnummer: 5

ISSN: 0031-6768

DOI Link: https://doi.org/10.1007/BF00388312

Verlag: Springer

Abstract: 
VIP caused a decrease in the diameter of rat colonic crypts. This decrease was followed by a volume increase at the middle and the upper third of the crypt, which finally led to an increase of diameter above initial control values. At the fundus only a cell shrinkage was observed. volume increase at the upper parts of the crypt was suppressed by the inhibitor of the Na+-K+-Cl--cotransporter, furosemide. When crypts were exposed to a hypertonic medium, cell shrinkage was followed by a regulatory volume increase at the middle and the upper third of the crypt but not at the fundus region. These results suggest a gradient in the distribution of the Na+-K+-Cl--cotransporter along the crypt axis.

Harvard-Zitierstil: Diener, M. (1994) Segmental differences along the crypt axis in the response of cell volume to secretagogues or hypotonic medium in the rat colon, Pflügers Archiv European Journal of Physiology, 426(5), pp. 462-464. https://doi.org/10.1007/BF00388312

APA-Zitierstil: Diener, M. (1994). Segmental differences along the crypt axis in the response of cell volume to secretagogues or hypotonic medium in the rat colon. Pflügers Archiv European Journal of Physiology. 426(5), 462-464. https://doi.org/10.1007/BF00388312