Journal article

Publication year: 2016

Journal: Scientific Reports

Volume number: 6

ISSN: 2045-2322

DOI Link: https://doi.org/10.1038/srep21841

Publisher: Nature Research

Abstract: 
Odors elicit complex patterns of activated olfactory sensory neurons. Knowing the complete olfactome, i.e. the responses in all sensory neurons for all relevant odorants, is desirable to understand olfactory coding. The DoOR project combines all available Drosophila odorant response data into a single consensus response matrix. Since its first release many studies were published: receptors were deorphanized and several response profiles were expanded. In this study, we add unpublished data to the odor-response profiles for four odorant receptors (Or10a, Or42b, Or47b, Or56a). We deorphanize Or69a, showing a broad response spectrum with the best ligands including 3-hydroxyhexanoate, alphaterpineol, 3-octanol and linalool. We include all of these datasets into DoOR, provide a comprehensive update of both code and data, and new tools for data analyses and visualizations. The DoOR project has a web interface for quick queries (http://neuro.uni.kn/DoOR), and a downloadable, open source toolbox written in R, including all processed and original datasets. DoOR now gives reliable odorant-responses for nearly all Drosophila olfactory responding units, listing 693 odorants, for a total of 7381 data points.

Harvard Citation style: Münch, D. and Galizia, C. (2016) DoOR 2.0-Comprehensive Mapping of Drosophila melanogaster Odorant Responses, Scientific Reports, 6, Article 21841. https://doi.org/10.1038/srep21841

APA Citation style: Münch, D., & Galizia, C. (2016). DoOR 2.0-Comprehensive Mapping of Drosophila melanogaster Odorant Responses. Scientific Reports. 6, Article 21841. https://doi.org/10.1038/srep21841