Journal article

Publication year: 2012

Pages: 171-182

Journal: Journal of Molecular Biochemistry

Volume number: 1

Issue number: 3

URL: https://www.jmolbiochem.com/index.php/JmolBiochem/article/view/60

Publisher: Lorem Ipsum Press

Abstract: 

The Cbl-associated protein/ponsin (CAP) is an adaptor protein that contains a so-called Sorbin homology
(SoHo) domain and three Src homology 3 (SH3) domains which are engaged in diverse protein-protein interactions. CAP has been shown to function in the regulation of the actin cytoskeleton and cell adhesion
and to be involved in the differentiation of muscle cells and adipocytes. In addition, it participates in signaling
pathways through several receptor tyrosine kinases such as insulin and neurotrophin receptors. In the last
couple of years, several studies have shed light on the details of these processes and identified novel interac-
tion partners of CAP. In this review, we summarize these recent findings and provide an overview on the
function of CAP especially in cell adhesion and membrane receptor signaling.

Harvard Citation style: Tomasovic, A., Kurrle, N., Banning, A. and Tikkanen, R. (2012) Role of Cbl-associated protein/ponsin in receptor tyrosine kinase signaling and cell adhesion, Journal of Molecular Biochemistry, 1(3), pp. 171-182. https://www.jmolbiochem.com/index.php/JmolBiochem/article/view/60

APA Citation style: Tomasovic, A., Kurrle, N., Banning, A., & Tikkanen, R. (2012). Role of Cbl-associated protein/ponsin in receptor tyrosine kinase signaling and cell adhesion. Journal of Molecular Biochemistry. 1(3), 171-182. https://www.jmolbiochem.com/index.php/JmolBiochem/article/view/60