Journalartikel
Autorenliste: Hosseini, A; Schreiner, PR
Jahr der Veröffentlichung: 2019
Seiten: 3746-3749
Zeitschrift: Organic Letters
Bandnummer: 21
Heftnummer: 10
ISSN: 1523-7060
DOI Link: https://doi.org/10.1021/acs.orglett.9b01192
Verlag: American Chemical Society
Abstract:
A new Kinugasa reaction protocol has been elaborated for the one-pot synthesis of 4-substituted beta-lactams utilizing calcium carbide and nitrone derivatives. Calcium carbide is thereby activated by TBAF center dot 3H(2)O in the presence of CuCl/NMI. The ease of synthesis and use of inexpensive chemicals provides rapid access of practical quantities of beta-lactams exclusively substituted at position 4.
Zitierstile
Harvard-Zitierstil: Hosseini, A. and Schreiner, P. (2019) Synthesis of Exclusively 4-Substituted beta-Lactams through the Kinugasa Reaction Utilizing Calcium Carbide, Organic Letters, 21(10), pp. 3746-3749. https://doi.org/10.1021/acs.orglett.9b01192
APA-Zitierstil: Hosseini, A., & Schreiner, P. (2019). Synthesis of Exclusively 4-Substituted beta-Lactams through the Kinugasa Reaction Utilizing Calcium Carbide. Organic Letters. 21(10), 3746-3749. https://doi.org/10.1021/acs.orglett.9b01192