Homologs of wingless and decapentaplegic display a complex and dynamic expression profile during appendage development in the millipede Glomeris marginata (Myriapoda: Diplopoda) - Research portal of Justus Liebig University Giessen:

Journal article

Homologs of wingless and decapentaplegic display a complex and dynamic expression profile during appendage development in the millipede Glomeris marginata (Myriapoda: Diplopoda)

Authors list: Prpic, NM

Publication year: 2004

Pages: 6-

Journal: Frontiers in Zoology

Volume number: 1

DOI Link: https://doi.org/10.1186/1742-9994-1-6

Publisher: BioMed Central

Abstract:
Background

The Drosophila genes wingless (wg) and decapentaplegic (dpp)
comprise the top level of a hierarchical gene cascade involved in
proximal-distal (PD) patterning of the legs. It remains unclear, whether
this cascade is common to the appendages of all arthropods. Here, wg and dpp are studied in the millipede Glomeris marginata, a representative of the Myriapoda.

Results

Glomeris wg (Gm-wg)
is expressed along the ventral side of the appendages compatible with
functioning during the patterning of both the PD and dorsal-ventral (DV)
axes. Gm-wg may also be involved in sensory organ formation in the gnathal appendages by inducing the expression of Distal-less (Dll) and H15 in the organ primordia. Expression of Glomeris dpp (Gm-dpp)
is found at the tip of the trunk legs as well as weakly along the
dorsal side of the legs in early stages. Taking data from other
arthropods into account, these results may be interpreted in favor of a
conserved mode of WG/DPP signaling. Apart from the main PD axis, many
arthropod appendages have additional branches (e.g. endites). It is
debated whether these extra branches develop their PD axis via the same
mechanism as the main PD axis, or whether branch-specific mechanisms
exist. Gene expression in possible endite homologs in Glomeris argues for the latter alternative.

Conclusion

All
available data argue in favor of a conserved role of WG/DPP morphogen
gradients in guiding the development of the main PD axis. Additional
branches in multibranched (multiramous) appendage types apparently do
not utilize the WG/DPP signaling system for their PD development. This
further supports recent work on crustaceans and insects, that lead to
similar conclusions.

Authors/Editors

- Uni.-Prof. Dr. Nikola Michael Prpic-Schäper

Citation Styles

Harvard Citation style: Prpic, N. (2004) Homologs of wingless and decapentaplegic display a complex and dynamic expression profile during appendage development in the millipede Glomeris marginata (Myriapoda: Diplopoda), Frontiers in Zoology, 1, p. 6. https://doi.org/10.1186/1742-9994-1-6

APA Citation style: Prpic, N. (2004). Homologs of wingless and decapentaplegic display a complex and dynamic expression profile during appendage development in the millipede Glomeris marginata (Myriapoda: Diplopoda). Frontiers in Zoology. 1, 6. https://doi.org/10.1186/1742-9994-1-6