Journal article
Authors list: Eckert, GP; Cairns, NJ; Müller, WE
Publication year: 1999
Pages: 757-761
Journal: Journal of Neural Transmission
Volume number: 106
Issue number: 7-8
ISSN: 0300-9564
DOI Link: https://doi.org/10.1007/s007020050196
Publisher: Springer
Abstract:
The in vitro effects of piracetam treatment on the fluidity of membranes from the hippocampus of Alzheimer's Disease patients (AD) and non-demented controls were studied. Hippocampal membranes of AD patients showed a significant lower hydrocarbon core fluidity compared with membranes from elderly non-demented controls. Preincubation with piracetam enhanced the hydrocarbon core fluidity of hippocampal membranes from AD-patients as well as elderly controls in a concentration depending fashion, although the effect was more pronounced for the AD membranes. In the presence of piracetam, the difference of the membrane fluidity between AD and control membranes was not longer apparent.
Citation Styles
Harvard Citation style: Eckert, G., Cairns, N. and Müller, W. (1999) Piracetam reverses hippocampal membrane alterations in Alzheimer's disease, Journal of Neural Transmission, 106(7-8), pp. 757-761. https://doi.org/10.1007/s007020050196
APA Citation style: Eckert, G., Cairns, N., & Müller, W. (1999). Piracetam reverses hippocampal membrane alterations in Alzheimer's disease. Journal of Neural Transmission. 106(7-8), 757-761. https://doi.org/10.1007/s007020050196
