Sammelbandbeitrag

Expression and regulation of thioredoxin reductases and other selenoproteins in bone


AutorenlisteJakob, F; Becker, K; Paar, E; Ebert-Duemig, R; Schütze, N

Erschienen inProtein Sensors and Reactive Oxygen Species - Part A: Selenoproteins and Thioredoxin

HerausgeberlisteHelmut, S; Lester, P

Jahr der Veröffentlichung2002

Seiten168-179

ISBN0-12-182248-6

eISBN978-0-12-182248-4

DOI Linkhttps://doi.org/10.1016/S0076-6879(02)47015-2

SerientitelMethods in Enzymology

Serienzählung347


Abstract

The expression of thioredoxin reductases and other selenoproteins in cells of the bone microenvironment may represent an important means of regulation of bone resorption and remodeling in health and disease. Selenoproteins and their substrates may influence intracellular and extracellular redox-dependent signaling, transcription factor activity, posttranslational modification of proteins, and general or compartmentalized scavenging from ROIs. However, the evaluation of their biological role in bone and their potential in terms of therapeutic approaches is just beginning.




Zitierstile

Harvard-ZitierstilJakob, F., Becker, K., Paar, E., Ebert-Duemig, R. and Schütze, N. (2002) Expression and regulation of thioredoxin reductases and other selenoproteins in bone, in Helmut, S. and Lester, P. (eds.) Protein Sensors and Reactive Oxygen Species - Part A: Selenoproteins and Thioredoxin. Amsterdam: Academic Press, pp. 168-179. https://doi.org/10.1016/S0076-6879(02)47015-2

APA-ZitierstilJakob, F., Becker, K., Paar, E., Ebert-Duemig, R., & Schütze, N. (2002). Expression and regulation of thioredoxin reductases and other selenoproteins in bone. In Helmut, S., & Lester, P. (Eds.), Protein Sensors and Reactive Oxygen Species - Part A: Selenoproteins and Thioredoxin (pp. 168-179). Academic Press. https://doi.org/10.1016/S0076-6879(02)47015-2



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