Conference paper

L-carnitine supplementation and the lipid metabolism of rats fed a hyperlipidemic diet


Authors listEder, K

Appeared inVitamine und Zusatzstoffe in der Ernährung von Mensch und Tier. 7. Symposium, 22. und 23. September 1999, Jena/Thüringen

Editor listSchubert, R.; Flachowsky, G.; Bitsch, R.; Jahreis, G.

Publication year1999

Pages487-490

ISBN3-934805-00-0

Conference7. Symposium Vitamine und Zusatzstoffe in der Ernährung von Mensch und Tier


Abstract
This study was conducted to investigate the effect of a dietary L-carnitine supplementation (500 mg per kg) on the lipid metabolism of adult rats fed a hyperlipidemic diet, After six weeks of feeding, there were no significant differences between the control group and the group receiving the diet supplemented with carnitine an parameters of animal performance (daily body weight gains and feed conversion ratio). The concentrations of triglycerides and phospholipids in plasma and individual lipoproteins as well as the concentrations of triglycerides, cholesterol and phospholipids in the liver were not significantly altered by dietary L-carnitine supplementation. The concentration of cholesterol in plasma and liver was even increased by dietary L-carnitine supplementation. The fatty acid composition of liver and erythrocyte membrane total lipids was also not considerably altered by dietary carnitine supplementation. In conclusion, this study does not indicate a lipid-lowering effect of dietary carnitine supplementation in hyperlipidemic rats, Probably, the essential functions of carnitine in metabolism were realized by carnitine which was synthesized endogenously.



Citation Styles

Harvard Citation styleEder, K. (1999) L-carnitine supplementation and the lipid metabolism of rats fed a hyperlipidemic diet, in Schubert, R., Flachowsky, G., Bitsch, R. and Jahreis, G. (eds.) Vitamine und Zusatzstoffe in der Ernährung von Mensch und Tier. 7. Symposium, 22. und 23. September 1999, Jena/Thüringen. Jena: Friedrich Schiller Universität. pp. 487-490

APA Citation styleEder, K. (1999). L-carnitine supplementation and the lipid metabolism of rats fed a hyperlipidemic diet. In Schubert, R., Flachowsky, G., Bitsch, R., & Jahreis, G. (Eds.), Vitamine und Zusatzstoffe in der Ernährung von Mensch und Tier. 7. Symposium, 22. und 23. September 1999, Jena/Thüringen. (pp. 487-490). Friedrich Schiller Universität.


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