The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis - Research portal of Justus Liebig University Giessen:

Journal article

The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis

Authors list: Carlier, A; Fehr, L; Pinto-Carbo, M; Schäberle, T; Reher, R; Dessein, S; König, G; Eberl, L

Publication year: 2016

Pages: 2507-2522

Journal: Environmental Microbiology

Volume number: 18

Issue number: 8

ISSN: 1462-2912

DOI Link: https://doi.org/10.1111/1462-2920.13184

Publisher: Wiley

Abstract:
A majority of Ardisia species harbour Burkholderia sp. bacteria within specialized leaf nodules. The bacteria are transmitted hereditarily and have not yet been cultured outside of their host. Because the plants cannot develop beyond the seedling stage without their symbionts, the symbiosis is considered obligatory. We sequenced for the first time the genome of CandidatusBurkholderia crenata (Ca.B. crenata), the leaf nodule symbiont of Ardisia crenata. The genome of Ca.B. crenata is the smallest Burkholderia genome to date. It contains a large amount of insertion sequences and pseudogenes and displays features consistent with reductive genome evolution. The genome does not encode functions commonly associated with plant symbioses such as nitrogen fixation and plant hormone metabolism. However, we identified unique genes with a predicted role in secondary metabolism in the genome of Ca. B. crenata. Specifically, we provide evidence that the bacterial symbionts are responsible for the synthesis of compound FR900359, a cyclic depsipeptide with biomedical properties previously isolated from leaves of A.crenata.

Authors/Editors

- Uni.-Prof. Dr. Till Friedrich Schäberle

Citation Styles

Harvard Citation style: Carlier, A., Fehr, L., Pinto-Carbo, M., Schäberle, T., Reher, R., Dessein, S., et al. (2016) The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis, Environmental Microbiology, 18(8), pp. 2507-2522. https://doi.org/10.1111/1462-2920.13184

APA Citation style: Carlier, A., Fehr, L., Pinto-Carbo, M., Schäberle, T., Reher, R., Dessein, S., König, G., & Eberl, L. (2016). The genome analysis of Candidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the Ardisia crenata leaf nodule symbiosis. Environmental Microbiology. 18(8), 2507-2522. https://doi.org/10.1111/1462-2920.13184