Some new features of Direct Analysis in Real Time mass spectrometry utilizing the desorption at an angle option - Forschungsportal der Justus-Liebig-Universität Gießen:

Journalartikel

Some new features of Direct Analysis in Real Time mass spectrometry utilizing the desorption at an angle option

Autorenliste: Chernetsova, E.S.; Revelsky, A.I.; Morlock, G.E.

Jahr der Veröffentlichung: 2011

Seiten: 2275-2282

Zeitschrift: Rapid Communications in Mass Spectrometry

Bandnummer: 25

Heftnummer: 16

DOI Link: https://doi.org/10.1002/rcm.5112

Verlag: Wiley

Abstract:

The present study is a first step towards the unexplored capabilities of Direct Analysis in Real Time (DART) mass spectrometry (MS) arising from the possibility of the desorption at an angle: scanning analysis of surfaces, including the coupling of thin-layer chromatography (TLC) with DART-MS, and a more sensitive analysis due to the preliminary concentration of analytes dissolved in large volumes of liquids on glass surfaces. In order to select the most favorable conditions for DART-MS analysis, proper positioning of samples is important. Therefore, a simple and cheap technique for the visualization of the impact region of the DART gas stream onto a substrate was developed. A filter paper or TLC plate, previously loaded with the analyte, was immersed in a derivatization solution. On this substrate, owing to the impact of the hot DART gas, reaction of the analyte to a colored product occurred. An improved capability of detection of DART-MS for the analysis of liquids was demonstrated by applying large volumes of model solutions of coumaphos into small glass vessels and drying these solutions prior to DART-MS analysis under ambient conditions. This allowed the introduction of, by up to more than two orders of magnitude, increased quantities of analyte compared with the conventional DART-MS analysis of liquids. Through this improved detectability, the capabilities of DART-MS in trace analysis could be strengthened. Copyright (C) 2011 John Wiley & Sons, Ltd.

Autoren/Herausgeber

- Uni.-Prof. Dr. Gertrud Elisabeth Morlock

Zitierstile

Harvard-Zitierstil: Chernetsova, E., Revelsky, A. and Morlock, G. (2011) Some new features of Direct Analysis in Real Time mass spectrometry utilizing the desorption at an angle option, Rapid Communications in Mass Spectrometry, 25(16), pp. 2275-2282. https://doi.org/10.1002/rcm.5112

APA-Zitierstil: Chernetsova, E., Revelsky, A., & Morlock, G. (2011). Some new features of Direct Analysis in Real Time mass spectrometry utilizing the desorption at an angle option. Rapid Communications in Mass Spectrometry. 25(16), 2275-2282. https://doi.org/10.1002/rcm.5112