Journalartikel

Jahr der Veröffentlichung: 2008

Seiten: 13-23

Zeitschrift: Clinical Science

Bandnummer: 115

Heftnummer: 1-2

ISSN: 0143-5221

DOI Link: https://doi.org/10.1042/CS20070226

Verlag: Portland Press

Abstract: 
Over the last few years, it has become obvious that obesity and insulin resistance are linked by a variety of proteins secreted by adipocytes. Visfatin/PBEF (pre-B-cell colony-enhancing factor) has recently been identified as a novel adipokine with insulin-mimetic effects. Furthermore, an enzymatic function has been reported that reveals visfatin/PBEF as Nampt (nicotinamide phosphoribosyltransferase; EC 2.4.2.12.). Moreover, reports on the structure and hormonal regulation of visfatin/PBEF/Nampt have given further insights into its potential physiological role. The present review summarizes studies on visfatin/PBEF/Nampt as a novel adipokine.

Harvard-Zitierstil: Sommer, G., Garten, A., Petzold, S., Beck-Sickinger, A., Blüher, M., Stumvoll, M., et al. (2008) Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine, Clinical Science, 115(1-2), pp. 13-23. https://doi.org/10.1042/CS20070226

APA-Zitierstil: Sommer, G., Garten, A., Petzold, S., Beck-Sickinger, A., Blüher, M., Stumvoll, M., & Fasshauer, M. (2008). Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. Clinical Science. 115(1-2), 13-23. https://doi.org/10.1042/CS20070226