Journalartikel
Autorenliste: von Wettstein, D; Rustgi, S; Kannangara, CG; Ankrah, N; Wen, S; Brew-Appiah, RAT; Wen, N; Gemini, R; Brueggeman, R; Reisenauer, P; Gill, KS; Liu, B; Pang, J; Wang, X; Claar, M; Langen, G; Kogel, KH
Jahr der Veröffentlichung: 2010
Seiten: 261-264
Zeitschrift: Annual wheat newsletter
Bandnummer: 56
URL: https://wheat.pw.usda.gov/ggpages/awn/
Verlag: Department of Agronomy, Kansas State University of Agriculture and Applied Science
Wheat and its products are potential elicitors for two types of immune responses in human beings: the first being the immunoglobulin E (IgE)-mediated occupational responses (e.g., bakers’ asthma) and the second being non-IgE-mediated responses due to ingestion of seed storage proteins of Triticeae (celiac disease). In general, wheat proteins also are poor in nutritional quality because of their imbalanced amino acid composition and deficiency of one of the essential amino acids, lysine. Among the known food allergy cases triggered by wheat and wheat products, most belong to celiac disease, constituting >24.4 million registered cases worldwide. The only effective therapy known to date is strict dietary adherence to a gluten-free diet, which often leads to nutritional deficiencies in celiac patients. In view of the above, we undertake a profound project with the ultimate objective of eliminating the prolamins from wheat grains that contain a majority of epitopes causing celiac disease. Eliminating these proteins also will address the issue of imbalance in the amino acid profile of wheat proteins.
Abstract:
Zitierstile
Harvard-Zitierstil: von Wettstein, D., Rustgi, S., Kannangara, C., Ankrah, N., Wen, S., Brew-Appiah, R., et al. (2010) A multipronged approach to develop nutritionally improved, celiac safe, wheat cultivars, Annual wheat newsletter, 56, pp. 261-264. https://wheat.pw.usda.gov/ggpages/awn/
APA-Zitierstil: von Wettstein, D., Rustgi, S., Kannangara, C., Ankrah, N., Wen, S., Brew-Appiah, R., Wen, N., Gemini, R., Brueggeman, R., Reisenauer, P., Gill, K., Liu, B., Pang, J., Wang, X., Claar, M., Langen, G., & Kogel, K. (2010). A multipronged approach to develop nutritionally improved, celiac safe, wheat cultivars. Annual wheat newsletter. 56, 261-264. https://wheat.pw.usda.gov/ggpages/awn/
