Journal article

Publication year: 2005

Pages: 185-192

Journal: Molecular Neurobiology

Volume number: 31

Issue number: 1-3

ISSN: 0893-7648

DOI Link: https://doi.org/10.1385/MN:31:1-3:185

Publisher: Springer

Abstract: 
There is considerable attention being given to the association of Alzheimer's disease and cholesterol homeostasis. To that end, some have suggested that elevated cholesterol levels are a risk factor for Alzheimer's disease. If elevated cholesterol is a risk factor for Alzheimer's disease, then it would be expected that patients with Alzheimer's disease would have elevated serum and brain cholesterol levels. Studies were reviewed that have examined cholesterol levels in Alzheimer's patients and control subjects, including prospective studies, and based on that review, the conclusion is reached that the majority of studies do not support elevated cholesterol levels in serum and brain as a risk factor for Alzheimer's disease. Alternative hypotheses are discussed, including cholesterol domains and subgroups of individuals with hypercholesteremia.

Harvard Citation style: Wood, W., Igbavboa, U., Eckert, G., Johnson-Anuna, L. and Müller, W. (2005) Is hypercholesterolemia a risk factor for Alzheimer's disease?, Molecular Neurobiology, 31(1-3), pp. 185-192. https://doi.org/10.1385/MN:31:1-3:185

APA Citation style: Wood, W., Igbavboa, U., Eckert, G., Johnson-Anuna, L., & Müller, W. (2005). Is hypercholesterolemia a risk factor for Alzheimer's disease?. Molecular Neurobiology. 31(1-3), 185-192. https://doi.org/10.1385/MN:31:1-3:185