Journal article

Publication year: 2020

Pages: 3385-3395

Journal: Chem

Volume number: 6

Issue number: 12

Open access status: Bronze

DOI Link: https://doi.org/10.1016/j.chempr.2020.10.003

Publisher: Cell Press

Abstract: 

Pyruvic acid represents a key molecule in prebiotic chemistry to form metabolites and amino acids. Without liquid water on the early Earth, endogenous formation of pyruvic acid is unlikely, and an exogenous delivery constitutes an appealing alternative. However, despite the detection of more than 200 molecules in space, pyruvic acid is elusive. Here, we describe its formation by barrierless recombination of hydroxycarbonyl (HOCO⋅) and acetyl (CH₃CO⋅) radicals in ices of acetaldehyde (CH₃CHO) and carbon dioxide (CO₂) modeling interstellar conditions driven by cosmic rays. Exploiting isotopically labeled ices and photoionization reflectron time-of-flight mass spectrometry, the reaction products were selectively photoionized in the temperature-programmed desorption phase and isomers discriminated based on their ionization energies. This reveals a key reaction pathway for pyruvic acid synthesis through non-equilibrium reactions in interstellar cold molecular clouds and star-forming regions, thus offering a unique entry point to abiotic organic synthesis in deep space.

Harvard Citation style: Kleimeier, N., Eckhardt, A., Schreiner, P. and Kaiser, R. (2020) Interstellar Formation of Biorelevant Pyruvic Acid (CH3COCOOH), Chem, 6(12), pp. 3385-3395. https://doi.org/10.1016/j.chempr.2020.10.003

APA Citation style: Kleimeier, N., Eckhardt, A., Schreiner, P., & Kaiser, R. (2020). Interstellar Formation of Biorelevant Pyruvic Acid (CH3COCOOH). Chem. 6(12), 3385-3395. https://doi.org/10.1016/j.chempr.2020.10.003