Journal article

Safety evaluation of a food enzyme containing chymosin, pepsin and gastricsin from the abomasum of suckling goats


Authors listLambre, C; Barat Baviera, JM; Bolognesi, C; Cocconcelli, PS; Crebelli, R; Gott, DM; Grob, K; Lampi, E; Mengelers, M; Mortensen, A; Riviere, G; Steffensen, IL; Tlustos, C; Van Loveren, H; Vernis, L; Zorn, H; Glandorf, B; Herman, L; Liu, Y; Maia, J; Chesson, A

Publication year2022

Pagese07005-

JournalEFSA Journal

Volume number20

Issue number1

DOI Linkhttps://doi.org/10.2903/j.efsa.2022.7005

PublisherWiley


Abstract
The food enzyme containing chymosin (EC 3.4.23.4), pepsin (EC 3.4.23.1) and gastricsin (EC 3.4.23.3) is prepared from the abomasum of suckling goats by Consejo Regulador de la Denominacion de Origen Queso Palmero and Consejo Regulador de la Denominacion de Origen Queso Majorero. The food enzyme is intended to be used in milk processing for cheese production. As no concerns arise from the animal source of the food enzyme, from its manufacture, and based on the history of safe use and consumption, the Panel considered that toxicological data were not required and no exposure assessment was necessary. Similarity of the amino acid sequences of the three proteins (chymosin, pepsin and gastricsin) to those of known allergens was searched and one match was found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is considered to be low. Based on the data provided, the Panel concludes that this food enzyme does not give rise to safety concerns under the intended conditions of use.



Authors/Editors




Citation Styles

Harvard Citation styleLambre, C., Barat Baviera, J., Bolognesi, C., Cocconcelli, P., Crebelli, R., Gott, D., et al. (2022) Safety evaluation of a food enzyme containing chymosin, pepsin and gastricsin from the abomasum of suckling goats, EFSA Journal, 20(1), p. e07005. https://doi.org/10.2903/j.efsa.2022.7005

APA Citation styleLambre, C., Barat Baviera, J., Bolognesi, C., Cocconcelli, P., Crebelli, R., Gott, D., Grob, K., Lampi, E., Mengelers, M., Mortensen, A., Riviere, G., Steffensen, I., Tlustos, C., Van Loveren, H., Vernis, L., Zorn, H., Glandorf, B., Herman, L., Liu, Y., ...Chesson, A. (2022). Safety evaluation of a food enzyme containing chymosin, pepsin and gastricsin from the abomasum of suckling goats. EFSA Journal. 20(1), e07005. https://doi.org/10.2903/j.efsa.2022.7005


Last updated on 2025-21-05 at 16:43