Journal article

Publication year: 2018

Pages: 5369-

Journal: Nature Communications

Volume number: 9

ISSN: 2041-1723

Open access status: Gold

DOI Link: https://doi.org/10.1038/s41467-018-07802-w

Publisher: Nature Research

Abstract: 
Bacterial flagella are helical proteinaceous fibers, composed of the protein flagellin, that confer motility to many bacterial species. The genomes of about half of all flagellated species include more than one flagellin gene, for reasons mostly unknown. Here we show that two flagellins (FlaA and FlaB) are spatially arranged in the polar flagellum of Shewanella putrefaciens, with FlaA being more abundant close to the motor and FlaB in the remainder of the flagellar filament. Observations of swimming trajectories and numerical simulations demonstrate that this segmentation improves motility in a range of environmental conditions, compared to mutants with single-flagellin filaments. In particular, it facilitates screw-like motility, which enhances cellular spreading through obstructed environments. Similar mechanisms may apply to other bacterial species and may explain the maintenance of multiple flagellins to form the flagellar filament.

Harvard Citation style: Kühn, M., Schmidt, F., Farthing, N., Rossmann, F., Helm, B., Wilson, L., et al. (2018) Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments, Nature Communications, 9, Article 5369. p. 5369. https://doi.org/10.1038/s41467-018-07802-w

APA Citation style: Kühn, M., Schmidt, F., Farthing, N., Rossmann, F., Helm, B., Wilson, L., Eckhardt, B., & Thormann, K. (2018). Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments. Nature Communications. 9, Article 5369, 5369. https://doi.org/10.1038/s41467-018-07802-w