Journal article

Publication year: 2022

Journal: PLoS ONE

Volume number: 17

Issue number: 7

ISSN: 1932-6203

Open access status: Gold

DOI Link: https://doi.org/10.1371/journal.pone.0270790

Publisher: Public Library of Science

Abstract: 
Fox genes represent an evolutionary old class of transcription factor encoding genes that evolved in the last common ancestor of fungi and animals. They represent key-components of multiple gene regulatory networks (GRNs) that are essential for embryonic development. Most of our knowledge about the function of Fox genes comes from vertebrate research, and for arthropods the only comprehensive gene expression analysis is that of the fly Drosophila melanogaster. For other arthropods, only selected Fox genes have been investigated. In this study, we provide the first comprehensive gene expression analysis of arthropod Fox genes including representative species of all main groups of arthropods, Pancrustacea, Myriapoda and Chelicerata. We also provide the first comprehensive analysis of Fox gene expression in an onychophoran species. Our data show that many of the Fox genes likely retained their function during panarthropod evolution highlighting their importance in development. Comparison with published data from other groups of animals shows that this high degree of evolutionary conservation often dates back beyond the last common ancestor of Panarthropoda.

Harvard Citation style: Janssen, R., Schomburg, C., Prpic, N. and Budd, G. (2022) A comprehensive study of arthropod and onychophoran Fox gene expression patterns, PLoS ONE, 17(7), Article e0270790. https://doi.org/10.1371/journal.pone.0270790

APA Citation style: Janssen, R., Schomburg, C., Prpic, N., & Budd, G. (2022). A comprehensive study of arthropod and onychophoran Fox gene expression patterns. PLoS ONE. 17(7), Article e0270790. https://doi.org/10.1371/journal.pone.0270790