Journalartikel

Jahr der Veröffentlichung: 2010

Seiten: 351-360

Zeitschrift: Chromosoma

Bandnummer: 119

Heftnummer: 4

ISSN: 0009-5915

Open Access Status: Hybrid

DOI Link: https://doi.org/10.1007/s00412-010-0262-0

Verlag: Springer

Abstract: 
More than 10(9) base pairs of the genome in higher eucaryotes are positioned in the interphase nucleus such that gene activation, gene repression, remote gene regulation by enhancer elements, and reading as well as adjusting epigenetic marks are possible. One important structural and functional component of chromatin organization is the zinc finger factor CTCF. Two decades of research has advanced the understanding of the fundamental role that CTCF plays in regulating such a vast expanse of DNA.

Harvard-Zitierstil: Ohlsson, R., Bartkuhn, M. and Renkawitz, R. (2010) CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin, Chromosoma, 119(4), pp. 351-360. https://doi.org/10.1007/s00412-010-0262-0

APA-Zitierstil: Ohlsson, R., Bartkuhn, M., & Renkawitz, R. (2010). CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin. Chromosoma. 119(4), 351-360. https://doi.org/10.1007/s00412-010-0262-0