Journalartikel

Safety evaluation of the food enzyme subtilisin from the non-genetically modified Bacillus paralicheniformis strain LMG S-30155


AutorenlisteEFSA CEP Panel; Lambré, C; Baviera, JMB; Bolognesi, C; Cocconcelli, PS; Crebelli, R; Gott, DM; Grob, K; Lampi, E; Mengelers, M; Mortensen, A; Rivière, G; Steffensen, IL; Tlustos, C; Van Loveren, H; Vernis, L; Zorn, H; Herman, L; Roos, Y; Andryszkiewicz, M; Fernàndez-Fraguas, C; Liu, Y; Peluso, S; Chesson, A

Jahr der Veröffentlichung2023

ZeitschriftEFSA Journal

Bandnummer21

Heftnummer6

ISSN1831-4732

DOI Linkhttps://doi.org/10.2903/j.efsa.2023.7910

VerlagWiley


Abstract

The food enzyme subtilisin (serine endopeptidase, EC 3.4.21.62) is produced with the non-genetically modified microorganism Bacillus paralicheniformis strain LMG S-30155 by ENMEX SA de CV, now part of Kerry Food Ingredients (Cork) Ltd. The food enzyme is intended to be used in oil production, hydrolysis of vegetable/microbial/animal proteins, yeast processing and production of flavouring preparations. The production strain of the food enzyme contains known antimicrobial resistance genes and genes involved in bacitracin biosynthesis. Consequently, it does not fulfil the requirements for the QPS approach to safety assessment. Bacitracin was detected in the food enzyme and the ■■■■■ The presence of bacitracin, a medically important antimicrobial, in the food enzyme represents a risk for the development of resistance in bacteria. Due to the presence of bacitracin, the Panel concluded that the food enzyme subtilisin produced with the non-genetically modified Bacillus paralicheniformis strain LMG S-30155 cannot be considered safe.




Autoren/Herausgeber




Zitierstile

Harvard-ZitierstilEFSA CEP Panel, Lambré, C., Baviera, J., Bolognesi, C., Cocconcelli, P., Crebelli, R., et al. (2023) Safety evaluation of the food enzyme subtilisin from the non-genetically modified Bacillus paralicheniformis strain LMG S-30155, EFSA Journal, 21(6), Article e07910. https://doi.org/10.2903/j.efsa.2023.7910

APA-ZitierstilEFSA CEP Panel, Lambré, C., Baviera, J., Bolognesi, C., Cocconcelli, P., Crebelli, R., Gott, D., Grob, K., Lampi, E., Mengelers, M., Mortensen, A., Rivière, G., Steffensen, I., Tlustos, C., Van Loveren, H., Vernis, L., Zorn, H., Herman, L., Roos, Y., ...Chesson, A. (2023). Safety evaluation of the food enzyme subtilisin from the non-genetically modified Bacillus paralicheniformis strain LMG S-30155. EFSA Journal. 21(6), Article e07910. https://doi.org/10.2903/j.efsa.2023.7910


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