Journal article
Authors list: Weidmann, M; Avsic-Zupanc, T; Bino, S; Bouloy, M; Burt, F; Chinikar, S; Christova, I; Dedushaj, I; El-Sanousi, A; Elaldi, N; Hewson, R; Hufert, FT; Humolli, I; van Vuren, PJ; Tufan, ZK; Korukluoglu, G; Lyssen, P; Mirazimi, A; Neyts, J; Niedrig, M; Ozkul, A; Papa, A; Paweska, J; Sall, AA; Schmaljohn, CS; Swanepoel, R; Uyar, Y; Weber, F; Zeller, H
Publication year: 2016
Pages: 2799-2808
Journal: Journal of General Virology
Volume number: 97
Issue number: 11
ISSN: 0022-1317
eISSN: 1465-2099
Open access status: Green
DOI Link: https://doi.org/10.1099/jgv.0.000610
Publisher: Microbiology Society
In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic countries out of necessity have had to perform diagnostic tests under biosafety level (BSL)-2 or -3 conditions. In particular, Turkey and several of the Balkan countries have safely processed more than 100 000 samples over many years in BSL-2 laboratories. It is therefore advocated that biosafety requirements for CCHF diagnostic procedures should be revised, to allow the tests required to be performed under enhanced BSL-2 conditions with appropriate biosafety laboratory equipment and personal protective equipment used according to standardized protocols in the countries affected. Downgrading of CCHFV research work from CL-4, BSL-4 to CL-3, BSL-3 should also be considered.
Abstract:
Citation Styles
Harvard Citation style: Weidmann, M., Avsic-Zupanc, T., Bino, S., Bouloy, M., Burt, F., Chinikar, S., et al. (2016) Biosafety standards for working with Crimean-Congo hemorrhagic fever virus , Journal of General Virology, 97(11), pp. 2799-2808. https://doi.org/10.1099/jgv.0.000610
APA Citation style: Weidmann, M., Avsic-Zupanc, T., Bino, S., Bouloy, M., Burt, F., Chinikar, S., Christova, I., Dedushaj, I., El-Sanousi, A., Elaldi, N., Hewson, R., Hufert, F., Humolli, I., van Vuren, P., Tufan, Z., Korukluoglu, G., Lyssen, P., Mirazimi, A., Neyts, J., ...Zeller, H. (2016). Biosafety standards for working with Crimean-Congo hemorrhagic fever virus . Journal of General Virology. 97(11), 2799-2808. https://doi.org/10.1099/jgv.0.000610