Journal article

Publication year: 2021

Journal: International Journal of Environmental Research and Public Health

Volume number: 18

Issue number: 11

eISSN: 1660-4601

Open access status: Gold

DOI Link: https://doi.org/10.3390/ijerph18115776

Publisher: MDPI

Abstract: 

The purpose of this study was to investigate blood-based biomarkers and their regulation with regard to different recovery-stress states. A total of 35 male elite athletes (13 badminton, 22 soccer players) were recruited, and two venous blood samples were taken: one in a 'recovered' state (REC) after a minimum of one-day rest from exercise and another one in a 'non-recovered' state (NOR) after a habitual loading microcycle. Overall, 23 blood-based biomarkers of different physiologic domains, which address inflammation, muscle damage, and tissue repair, were analyzed by Luminex assays. Across all athletes, only creatine kinase (CK), interleukin (IL-) 6, and IL-17A showed higher concentrations at NOR compared to REC time points. In badminton players, higher levels of CK and IL-17A at NOR were found. In contrast, a higher value for S100 calcium-binding protein A8 (S100A8) at REC was found in badminton players. Similar differences were found for BDNF in soccer players. Soccer players also showed increased levels of CK, and IL-6 at NOR compared to REC state. Several molecular markers were shown to be responsive to differing recovery-stress states, but their suitability as biomarkers in training must be further validated.

Harvard Citation style: Hacker, S., Reichel, T., Hecksteden, A., Weyh, C., Gebhardt, K., Pfeiffer, M., et al. (2021) Recovery-Stress Response of Blood-Based Biomarkers, International Journal of Environmental Research and Public Health, 18(11), Article 5776. https://doi.org/10.3390/ijerph18115776

APA Citation style: Hacker, S., Reichel, T., Hecksteden, A., Weyh, C., Gebhardt, K., Pfeiffer, M., Ferrauti, A., Kellmann, M., Meyer, T., & Krüger, K. (2021). Recovery-Stress Response of Blood-Based Biomarkers. International Journal of Environmental Research and Public Health. 18(11), Article 5776. https://doi.org/10.3390/ijerph18115776