Journalartikel

A randomized controlled trial examining the effects of 16 weeks of moderate-to-intensive cycling and honey supplementation on lymphocyte oxidative DNA damage and cytokine changes in male road cyclists


AutorenlisteMaleki, Behzad Hajizadeh; Tartibian, Bakhtyar; Mooren, Frank C.; Krüger, Karsten; FitzGerald, Leah Z.; Chehrazi, Mohammad

Jahr der Veröffentlichung2016

Seiten222-231

ZeitschriftCytokine

Bandnummer88

ISSN1043-4666

eISSN1096-0023

DOI Linkhttps://doi.org/10.1016/j.cyto.2016.09.016

VerlagElsevier


Abstract

The aim of this study was to investigate whether honey supplementation (70 g, ninety minutes before each training session) attenuates changes in lymphocyte counts, DNA damage, cytokines, antioxidative and peroxidative biomarkers following moderate-to-intensive exercise training in male road cyclists. Healthy nonprofessional cyclists (n = 24, aged 17-26 years) were randomly assigned to exercise + supplement (EX + S, n = 12) and exercise (EX, n =.12) groups for an experimental period of 16 weeks. Moderate to -intensive exercise training increased lymphocytes DNA damage, cytokines and peroxidative biomarkers as well as decreased antioxidative biomarkers in the EX group. These changes were significantly attenuated in the EX + S group. Furthermore, for both groups the observed changes in peroxidative and antioxidative biomarkers could be correlated positively and negatively, respectively, with lymphocyte DNA damage and cytokines. Findings suggest that honey attenuates oxidative stress and lymphocyte DNA damage after exercise, activities that are most likely attributable to its high antioxidant capacity.




Autoren/Herausgeber




Zitierstile

Harvard-ZitierstilMaleki, B., Tartibian, B., Mooren, F., Krüger, K., FitzGerald, L. and Chehrazi, M. (2016) A randomized controlled trial examining the effects of 16 weeks of moderate-to-intensive cycling and honey supplementation on lymphocyte oxidative DNA damage and cytokine changes in male road cyclists, Cytokine, 88, pp. 222-231. https://doi.org/10.1016/j.cyto.2016.09.016

APA-ZitierstilMaleki, B., Tartibian, B., Mooren, F., Krüger, K., FitzGerald, L., & Chehrazi, M. (2016). A randomized controlled trial examining the effects of 16 weeks of moderate-to-intensive cycling and honey supplementation on lymphocyte oxidative DNA damage and cytokine changes in male road cyclists. Cytokine. 88, 222-231. https://doi.org/10.1016/j.cyto.2016.09.016



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