Uni.-Prof. Dr. Marek Bartkuhn
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ORCID: https://orcid.org/0000-0001-6872-9082 Researcher ID: GDF-8898-2022 |
Projekte als Projektleitung
- FOR 5644 INFINITE TP Z1 - Die Rolle von Immunzellen in der Funktion des normalen und pathologisch veränderten Hoden und Nebenhoden - Teilprojekt: Entschlüsselung der Funktion von Immunzellen in Hoden und Nebenhoden durch Einzelzelltranskriptomik, räumliche aufgelöste Proteomik und integrative Bioinformatik
01.08.2024 - 31.07.2028
Deutsche Forschungsgemeinschaft (DFG) - TRR 81 Z01 - Chromatin-Veränderungen in Differenzierung und Malignität. Bioinformatische Analyse genomweiter Datensätze
01.07.2010 - 30.06.2022
Deutsche Forschungsgemeinschaft (DFG)
Projekte als Co-Investigator oder weiteres Projektmitglied
- Nukleosom-Präservierung in Säugetier-Spermien: ein epigenetisches Programm zur Wahrung der gesunden männlichen Reproduktion
01.01.2015 - 31.12.2020
Deutsche Forschungsgemeinschaft (DFG)
Publikationen
6 von 7
- The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner (2012)
- Epigenetics and Chromatin
Journalartikel - The relevance of acetylated histone H4 at lysine 12 (H4K12ac) for RNA transcripts in human spermatozoa, mouse pronucleus formation and parthenogenetic activation of murine oocytes (2012)
- European Urology SupplementsReproduction, Fertility and Development
Meeting Abstract - Co-Localisation of two active epigenetic histone marks, H4K12ac and H3K9ac, in gene promoters of spermatozoa from fertile donors and subfertile patients
- European Urology Supplements
Meeting Abstract - Presence of histone H3 acetylated at lysine 9 in male germ cells and its distribution pattern in the genome of human spermatozoa (2011)
Journalartikel - CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin (2010)
- ChromosomaEuropean Urology Supplements
Journalartikel - Modular Insulators: Genome Wide Search for Composite CTCF/Thyroid Hormone Receptor Binding Sites (2010)
- PLoS ONE
Journalartikel - The accessibility of human sperm chromatin for H4K12ac-bindings is not limited by DNA methylation (2010)
Meeting Abstract - The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men (2010)
- Reproduction
Journalartikel - Acetylated histone H4K12 exhibits different binding to sperm DNA between fertile men and infertile patients (2009)
- European Urology Supplements
Meeting Abstract - Active promoters and insulators are marked by the centrosomal protein 190 (2009)
- The EMBO Journal
Journalartikel - Colocalisation of different modified histones within BRDT gene locus of sperm DNA from fertile and infertile men (2009)Differential binding pattern of acetylated histone H4 at lysin 12 (H4K12ac) to the sperm DNA between healthy donors and infertile patients (2009)
- European Urology SupplementsJournal of Andrology
Meeting Abstract- Long range chromatin interactions involved in gene regulation (2008)
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Journalartikel - CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex (2007)
- PLoS Genetics
Journalartikel - Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation (2007)
- BMC Developmental Biology
Journalartikel
