Uni.-Prof. Dr. Joachim Matthias Johannes Geyer

Projekte als Projektleitung

  

  

  

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• Structure-based drug development of virus-selective HBV/HDV entry inhibitors by virtual screening in collaboration with the company ChemSpace
  01.07.2024 - 28.02.2026
  Hessisches Ministerium für Wissenschaft und Forschung, Kunst und Kultur (HMWK)
• Philipp Schwartz-Stipendium der Alexander von Humboldt-Stiftung/Verlängerung Prof. Dr. Emre Karakus
  01.08.2021 - 31.07.2022
  Alexander von Humboldt-Stiftung (AvH)
• Stipendium Emre Karakus - Scholar Rescue Fund
  01.08.2018 - 31.07.2019
  Justus-Liebig-Universität Gießen (JLU)
• Kooperationsvertrag BVL: Pharmakovigilanz – Instrument zur Überwachung und Betreuung von Tierarzneimitteln
  17.05.2018 - 17.05.2020
  Bundesamt für Verbraucherschutz und Lebensmittelsicherheit (BVL)
• SFB 1021 TP B08* - RNA-Viren: Metabolismus viraler RNA, Immunantwort der Wirtszellen und virale Pathogenese - Teilprojekt: Interaktionen des Hepatitis-D-Virus (HDV) mit seinem Helfervirus (HBV) und seinem Rezeptor NTCP in einem in vitro Infektionsmodell
  01.01.2017 - 31.03.2021
  Deutsche Forschungsgemeinschaft (DFG)

Publikationen

  

  

  

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• The role of sulfated steroid hormones in reproductive processes (2017) (2015)
  
  • The Journal of Steroid Biochemistry and Molecular BiologyJournal of Veterinary Pharmacology and Therapeutics
  Geyer, J; Bakhaus, K; Bernhardt, R; et al.
  Journalartikel
• Current insights into the sulfatase pathway in human testis and cultured Sertoli cells (2016)
  
  • Histochemistry and Cell Biology
  Hartmann, K; Bennien, J; Wapelhorst, B; et al.
  Journalartikel
• Detection of novel polymorphisms in the ckit gene of canine patients with lymphoma, melanoma, haemangiosarcoma, and osteosarcoma (2016)
  
  • Veterinary Research Communications
  Gramer, I; Kessler, M; Geyer, J
  Journalartikel
• Identification of novel inhibitors of the steroid sulfate carrier 'sodium-dependent organic anion transporter' SOAT (SLC10A6) by pharmacophore modelling (2016)2015)
  
  • Molecular and Cellular Endocrinology
  Grosser, G; Baringhaus, KH; Döring, B; et al.
  Journalartikel
• Brain penetration of emodepside is increased in P-glycoprotein-deficient mice and leads to neurotoxicosis
  
  Elmshaeuser, S; Straehle, LC; Kranz, J; et al.
  Journalartikel
• Determination of MDR1 gene expression for prediction of chemotherapy tolerance and treatment outcome in dogs with lymphoma (2015)
  
  • Veterinary and Comparative Oncology
  Gramer, I; Kessler, M; Geyer, J
  Journalartikel
• Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes (
  
  • BMC Neuroscience
  Schmidt, S; Moncada, M; Burger, S; et al. Journalartikel
• Transfection of Sertoli cells with androgen receptor alters gene expression without androgen stimulation (2015)
  
  • BMC Molecular Biology
  Fietz, D; Markmann, M; Lang, D; et al.
  Journalartikel
• Transport of the soy isoflavone daidzein and its conjugative metabolites by the carriers SOAT, NTCP, OAT4, and OATP2B1 (2015)
  
  • Archives of Toxicology
  Grosser, G; Döring, B; Ugele, B; et al.
  Journalartikel
• Arzneimittelunverträglichkeiten nach Gabe von Emodepsid/Praziquantel (Profender®) bei Hunden mit MDR1-Gendefekt (2014)
  
  • Kleintierpraxis
  Elmshäuser, S; Wilke, A; Geyer, J
  Journalartikel
• A steroidogenic pathway for sulfonated steroids: The metabolism of pregnenolone sulfate (2014)2014)
  
  • The Journal of Steroid Biochemistry and Molecular BiologyJournal of Hepatology
  Neunzig, J; Sánchez-Guijo, A; Mosa, A; et al.
  Journalartikel
• Kinetics of the bile acid transporter and hepatitis B virus receptor Na+/taurocholate cotransporting polypeptide (NTCP) in hepatocytes
  
  König, A; Döring, B; Mohr, C; et al.
  Journalartikel
• Stress-Induced Upregulation of SLC19A3 is Impaired in Biotin-Thiamine-Responsive Basal Ganglia Disease (2014)
  
  • Brain Pathology
  Schänzer, A; Döring, B; Ondrouschek, M; et al.
  Journalartikel
• The role of the efflux carriers Abcg2 and Abcc2 for the hepatobiliary elimination of benzo[a]pyrene and its metabolites in mice (2014)
  
  • Chemico-Biological Interactions: A journal of molecular, cellular and biochemical toxicologyThe Journal of Steroid Biochemistry and Molecular Biology
  Kranz, J; Hessel, S; Aretz, J; et al.
  Journalartikel
• Transport of the placental estriol precursor 16α-hydroxy-dehydroepiandrosterone sulfate (16α-OH-DHEAS) by stably transfected OAT4-, SOAT-, and NTCP-HEK293 cells (2014)
  
  Schweigmann, H; Sánchez-Guijo, A; Ugele, B; et al.
  Journalartikel