Journalartikel

Autofocusing MALDI mass spectrometry imaging of tissue sections and 3D chemical topography of nonflat surfaces


AutorenlisteKompauer, M; Heiles, S; Spengler, B

Jahr der Veröffentlichung2017

Seiten1156-1158

ZeitschriftNature Methods

Bandnummer14

Heftnummer12

ISSN1548-7091

DOI Linkhttps://doi.org/10.1038/nmeth.4433

VerlagNature Research


Abstract
We describe an atmospheric pressure matrix-assisted laser desorption-ionization mass spectrometry imaging system that uses long-distance laser triangulation on a micrometer scale to simultaneously obtain topographic and molecular information from 3D surfaces. We studied the topographic distribution of compounds on irregular 3D surfaces of plants and parasites, and we imaged nonplanar tissue sections with high lateral resolution, thereby eliminating height-related signal artifacts.



Zitierstile

Harvard-ZitierstilKompauer, M., Heiles, S. and Spengler, B. (2017) Autofocusing MALDI mass spectrometry imaging of tissue sections and 3D chemical topography of nonflat surfaces, Nature Methods, 14(12), pp. 1156-1158. https://doi.org/10.1038/nmeth.4433

APA-ZitierstilKompauer, M., Heiles, S., & Spengler, B. (2017). Autofocusing MALDI mass spectrometry imaging of tissue sections and 3D chemical topography of nonflat surfaces. Nature Methods. 14(12), 1156-1158. https://doi.org/10.1038/nmeth.4433



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