Journal article
Authors list: Foerster, Kai; Ertl-Wagner, Birgit; Ehrhardt, Harald; Busen, Hannah; Sass, Steffen; Pomschar, Andreas; Naehrlich, Lutz; Schulze, Andreas; Flemmer, Andreas W.; Huebener, Christoph; Eickelberg, Oliver; Theis, Fabian; Dietrich, Olaf; Hilgendorff, Anne
Publication year: 2020
Pages: 184-187
Journal: Thorax
Volume number: 75
Issue number: 2
ISSN: 0040-6376
eISSN: 1468-3296
Open access status: Green
DOI Link: https://doi.org/10.1136/thoraxjnl-2018-212384
Publisher: BMJ Publishing Group
Abstract:
We developed a MRI protocol using transverse (T2) and longitudinal (T1) mapping sequences to characterise lung structural changes in preterm infants with bronchopulmonary dysplasia (BPD). We prospectively enrolled 61 infants to perform 3-Tesla MRI of the lung in quiet sleep. Statistical analysis was performed using logistic Group Lasso regression and logistic regression. Increased lung T2 relaxation time and decreased lung T1 relaxation time indicated BPD yielding an area under the curve (AUC) of 0.80. Results were confirmed in an independent study cohort (AUC 0.75) and mirrored by lung function testing, indicating the high potential for MRI in future BPD diagnostics.
Citation Styles
Harvard Citation style: Foerster, K., Ertl-Wagner, B., Ehrhardt, H., Busen, H., Sass, S., Pomschar, A., et al. (2020) Altered relaxation times in MRI indicate bronchopulmonary dysplasia, Thorax, 75(2), pp. 184-187. https://doi.org/10.1136/thoraxjnl-2018-212384
APA Citation style: Foerster, K., Ertl-Wagner, B., Ehrhardt, H., Busen, H., Sass, S., Pomschar, A., Naehrlich, L., Schulze, A., Flemmer, A., Huebener, C., Eickelberg, O., Theis, F., Dietrich, O., & Hilgendorff, A. (2020). Altered relaxation times in MRI indicate bronchopulmonary dysplasia. Thorax. 75(2), 184-187. https://doi.org/10.1136/thoraxjnl-2018-212384
Keywords
MAGNETIC-RESONANCE
