Journalartikel

Prospective quality control study of a novel gravity-driven whole blood separation system suitable for humanitarian crises


AutorenlisteHackstein, H.; Moeller, A.; Gerlach, M.; Sachs, U.; Bein, G.

Jahr der Veröffentlichung2017

Seiten806-809

ZeitschriftVox Sanguinis

Bandnummer112

Heftnummer8

ISSN0042-9007

eISSN1423-0410

DOI Linkhttps://doi.org/10.1111/vox.12595

VerlagWiley


Abstract
Centrifugation-based whole blood (WB) separation represents the worldwide standard but it depends on electricity and infrastructure. We have prospectively evaluated a novel hollow-fibre WB separation system that does not require manual priming or blood flow regulation (n = 29). RBC units contained sufficient Hb (504 g +/- 43), low leucocytes (90 000 +/- 0008), exhibited low haemolysis (057% +/- 049) and robust ATP content (5147% +/- 82) after 43 days storage. Plasma units contained low leucocytes and mean coagulation factor activities for FV, FVIII and FXI were 47%, 90% and 68%, respectively. RBC met quality specifications but plasma units exhibited reduced FV and FXI activity.



Zitierstile

Harvard-ZitierstilHackstein, H., Moeller, A., Gerlach, M., Sachs, U. and Bein, G. (2017) Prospective quality control study of a novel gravity-driven whole blood separation system suitable for humanitarian crises, Vox Sanguinis, 112(8), pp. 806-809. https://doi.org/10.1111/vox.12595

APA-ZitierstilHackstein, H., Moeller, A., Gerlach, M., Sachs, U., & Bein, G. (2017). Prospective quality control study of a novel gravity-driven whole blood separation system suitable for humanitarian crises. Vox Sanguinis. 112(8), 806-809. https://doi.org/10.1111/vox.12595



Schlagwörter


blood component productionblood processingfresh frozen plasma


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