Journal article

Publication year: 2017

Pages: 806-809

Journal: Vox Sanguinis

Volume number: 112

Issue number: 8

ISSN: 0042-9007

eISSN: 1423-0410

DOI Link: https://doi.org/10.1111/vox.12595

Publisher: Wiley

Abstract: 
Centrifugation-based whole blood (WB) separation represents the worldwide standard but it depends on electricity and infrastructure. We have prospectively evaluated a novel hollow-fibre WB separation system that does not require manual priming or blood flow regulation (n = 29). RBC units contained sufficient Hb (504 g +/- 43), low leucocytes (90 000 +/- 0008), exhibited low haemolysis (057% +/- 049) and robust ATP content (5147% +/- 82) after 43 days storage. Plasma units contained low leucocytes and mean coagulation factor activities for FV, FVIII and FXI were 47%, 90% and 68%, respectively. RBC met quality specifications but plasma units exhibited reduced FV and FXI activity.

Harvard Citation style: Hackstein, H., Moeller, A., Gerlach, M., Sachs, U. and Bein, G. (2017) Prospective quality control study of a novel gravity-driven whole blood separation system suitable for humanitarian crises, Vox Sanguinis, 112(8), pp. 806-809. https://doi.org/10.1111/vox.12595

APA Citation style: Hackstein, H., Moeller, A., Gerlach, M., Sachs, U., & Bein, G. (2017). Prospective quality control study of a novel gravity-driven whole blood separation system suitable for humanitarian crises. Vox Sanguinis. 112(8), 806-809. https://doi.org/10.1111/vox.12595